Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 6/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305394 | 0.90 | CXCR2 (0.44) | CRHR1CXCR2DPP4PDE5APDE9A | |
| SCHEMBL2865706 | 0.90 | CXCR2 (0.44) | CRHR1CXCR2DPP4PDE5APDE9A | |
| SCHEMBL3420435 | 0.89 | CRHR1 (0.38) | CRHR1DPP4EGFRERBB2 | |
| SCHEMBL3422838 | 0.87 | CRHR1 (0.37) | CRHR1DPP4EGFRERBB2 | |
| SCHEMBL13476252 | 0.86 | CCNE2 (0.43) | CRHR1CXCR2EGFRERBB2CNR1 | |
| SCHEMBL1747656 | 0.86 | CRHR1 (0.44) | CRHR1CXCR2DPP4EGFRERBB2 | |
| SCHEMBL31305532 | 0.86 | CRHR1 (0.44) | CRHR1CXCR2DPP4EGFRERBB2 | |
| SCHEMBL28813824 | 0.85 | CRHR1 (0.40) | CRHR1DPP4EGFRERBB2 | |
| SCHEMBL3420391 | 0.84 | CRHR1 (0.37) | CRHR1CXCR2DPP4EGFRERBB2 | |
| SCHEMBL3423129 | 0.84 | CRHR1 (0.37) | CRHR1CXCR2DPP4EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010041614-A1 | 2-BENZYL-4-(2,4-DICHLOROPHENYL)-5-METHYLIMIDAZOLE COMPOUND | SHIKOKU CHEMICALS CORPORATION (JP) | 2010-04-15 | — | — | WO | disclosed |