SCHEMBL3419804

SCHEMBL3419804

C=CC(=O)OCCC[Si](CC)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 2/20 0.52
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.38
HCAR2 Q8TDS4 3/20 0.34
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7270699 0.86 TSHR (0.50) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL534067 0.85 TSHR (0.58) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28183076 0.84 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL534222 0.84 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL1066391 0.83 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL331043 0.81 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL712918 0.81 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL374776 0.81 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL344379 0.81 TSHR (0.57) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL9226807 0.81 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1588829-B1 Method for preparing a mold part useful for transfering a coating onto an optical substrate ESSILOR INT (FR) 2020-08-26 EP claimed
JP-4551620-B2 2010-09-29 JP claimed
JP-4118144-B2 2008-07-16 JP claimed
EP-1401634-B1 METHOD FOR TRANSFERRING FROM A MOLD A HYDROPHOBIC TOP COAT ONTO AN OPTICAL SUBSTRATE ESSILOR INT (FR) 2006-10-04 EP claimed
EP-1395417-B1 METHOD FOR FORMING ON-SITE A COATED OPTICAL ARTICLE ESSILOR INT (FR) 2006-08-02 EP claimed
US-6986857-B2 Method for preparing a mold part useful for transferring a coating onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2006-01-17 US claimed
EP-1588829-A2 Method for preparing a mold part useful for transfering a coating onto an optical substrate ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) 2005-10-26 EP claimed
US-6890458-B2 Method for forming on-site a coated optical article ESSILOR INTERNATIONAL COMPAGNIE GENERAL D'OPTIQUE (FR) 2005-05-10 US claimed
US-6887402-B2 Method for transferring from a mold a hydrophobic top coat onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERAL D'OPTIQUE (FR) 2005-05-03 US claimed
JP-2004526606-A 2004-09-02 JP claimed
JP-2004526605-A 2004-09-02 JP claimed
US-20040065968-A1 Method for preparing a mold part useful for transferring a coating onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE 2004-04-08 US claimed
EP-1401634-A1 METHOD FOR TRANSFERRING FROM A MOLD A HYDROPHOBIC TOP COAT ONTO AN OPTICAL SUBSTRATE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2004-03-31 EP claimed
EP-1395417-A2 METHOD FOR FORMING ON-SITE A COATED OPTICAL ARTICLE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2004-03-10 EP claimed
US-20030122269-A1 Method for forming on-site a coated optical article ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-07-03 US claimed
US-20030116872-A1 Method for transferring from a mold a hydrophobic top coat onto an optical substrate ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2003-06-26 US claimed
WO-2002096628-A2 METHOD FOR FORMING ON-SITE A COATED OPTICAL ARTICLE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-12-05 WO claimed
WO-2002096627-A1 METHOD FOR TRANSFERRING FROM A MOLD A HYDROPHOBIC TOP COAT ONTO AN OPTICAL SUBSTRATE. ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-12-05 WO claimed
CN-102196800-B Dispersion of soft polymer particles, cosmetic composition comprising same and cosmetic treatment method OREAL 2015-06-17 CN disclosed