SCHEMBL374776

SCHEMBL374776

C=CC(=O)OCCC[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.57
ALDH1A1 P00352 4/20 0.57
CYP3A4 P08684 2/20 0.57
HPGD P15428 1/20 0.56
TP53 P04637 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 1/20 0.47
THRB P10828 2/20 0.40
ATM Q13315 1/20 0.37
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302541 0.95 TSHR (0.60) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL332090 0.95 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL18554566 0.93 TSHR (0.63) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9764152 0.92 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL14175495 0.91 TSHR (0.55) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL19566739 0.91 TSHR (0.47) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10890672 0.90 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9763730 0.90 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL17069795 0.90 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL9122872 0.89 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2764065-B1 SACRIFICIAL ADHESIVE COATINGS ROCHAL IND LLC (US) 2017-03-22 EP claimed
EP-2764065-A1 SACRIFICIAL ADHESIVE COATINGS Rochal Industries, LLP (US) 2014-08-13 EP claimed
WO-2013052276-A1 SACRIFICIAL ADHESIVE COATINGS ROCHAL INDUSTRIES, LLP (US) 2013-04-11 WO claimed
US-8263720-B1 Sacrificial adhesive coatings ROCHAL INDUSTRIES, LLP (US) 2012-09-11 US claimed
EP-1425321-A2 BEADED POLYETHYLENE GLYCOL-BASED RESINS Carlsberg A/S (DK) 2004-06-09 EP claimed
WO-2003025039-A2 BEADED POLYETHYLENE GLYCOL-BASED RESINS CARLSBERG A/S (DK) 2003-03-27 WO claimed
US-20030050415-A1 Beaded polyethylene glycol-based resins CARLSBERG A/S (DK) 2003-03-13 US claimed
EP-0348106-B1 MONOMERIC COMPOSTION AND POLYMER THEREFROM Shin-Etsu Chemical Co., Ltd. (JP) 1993-04-28 EP claimed
US-4988788-A Room temperature-curable coating composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-01-29 US claimed
US-4910278-A Blend of a organosiloxy containing acrylated ester and another acrylated ester SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-03-20 US claimed
EP-0348106-A2 Monomeric compostion and polymer therefrom Shin-Etsu Chemical Co., Ltd. (JP) 1989-12-27 EP claimed
US-20260015525-A1 ARTICLE FIXTURE, METHOD FOR REMOVING ARTICLE, AND ADHESIVE SHEET UNIT SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-15 US disclosed
EP-4561513-A1 ARTICLE FIXTURE, METHOD FOR REMOVING ARTICLE, AND ADHESIVE SHEET UNIT Solventum Intellectual Properties Company (US) 2025-06-04 EP disclosed
CN-119630371-A Article fixing device, method for removing article, and adhesive sheet unit 舒万诺知识产权公司 2025-03-14 CN disclosed
EP-3650514-B1 ULTRAVIOLET CURABLE SILICONE ADHESIVE COMPOSITION AND SILICONE ADHESIVE FILM SHINETSU CHEMICAL CO (JP) 2024-09-18 EP disclosed
EP-0294515-A2 Contact lens material Menicon Co., Ltd. (JP) 1988-12-14 EP disclosed
US-4743667-A ACRYLATED SILOXXANES, OXYGEN PERMEABLE NIPPON CONTACT LENS, INC. (JP) 1988-05-10 US disclosed
US-4718748-A CURABLE POLYSILOXANE U.S. PHILIPS CORPORATION (US) 1988-01-12 US disclosed
US-4594401-A Oxygen permeable hard contact lens formed from styrene monomer containing a silyl or siloxane group SHIN-ETSU CHEMICAL CO., LTD. (JP) 1986-06-10 US disclosed
US-4433125-A COPOLYMER OF SILICON CONTAINING ACRYLATE OR METHACRYLATE, AND FLUOROALKYL ACRYLATE OR METHACRYLATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1984-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015525-A1 ARTICLE FIXTURE, METHOD FOR REMOVING ARTICLE, AND ADHESIVE SHEET UNIT STUB1, TLN1, ICAM1 TSHR 1544/4885ALDH1A1 1950/4885CYP3A4 4738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.