Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243433 | 0.79 | KDM4E (0.50) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL320940 | 0.77 | PRMT1 (0.58) | — | |
| Glutarodihydroxamic Acid SCHEMBL11768782 | 0.76 | HDAC1 (0.81) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL3174690 | 0.76 | KDM4E (0.50) | KDM4E | |
| SCHEMBL8958360 | 0.76 | KDM4E (0.43) | KDM4E | |
| SCHEMBL11768749 | 0.76 | HDAC1 (0.93) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| Azelaic Bis Hydroxamic Acid SCHEMBL4741072 | 0.73 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC2HDAC6 | |
| SCHEMBL15871737 | 0.73 | KDM4E (0.55) | KDM4E | |
| SCHEMBL20836564 | 0.73 | KDM4E (0.55) | KDM4E | |
| SCHEMBL10439098 | 0.73 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282876-A1 | URICASE-ALBUMIN CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Proabtech Inc. (KR) | 2023-11-29 | — | — | EP | disclosed |
| WO-2010065709-A2 | HYDROXAMIC ACID DERIVATIVES, PREPARATION AND THERAPEUTIC USES THEREOF | KHAN AMIN (US) | 2010-06-10 | — | — | WO | disclosed |