SCHEMBL8958360

SCHEMBL8958360

O=C(O)NCCCNC(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.43
HIF1A Q16665 1/20 0.43
PRMT1 Q99873 1/20 0.42
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP2D6 P10635 1/20 0.41
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
POLB P06746 1/20 0.39
CA1 P00915 1/20 0.39
ADRA1A P35348 1/20 0.39
CA3 P07451 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3174690 0.93 KDM4E (0.50) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL3483791 0.91 CA3 (0.50) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL28569684 0.90 KDM4E (0.55) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL20836564 0.90 KDM4E (0.55) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL30541972 0.90 KDM4E (0.55) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL2029681 0.90 KDM4E (0.55) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL15871737 0.90 KDM4E (0.55) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL453216 0.90 KDM4E (0.55) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL5569558 0.90 KDM4E (0.55) KDM4EMAPK1HIF1APRMT1ALDH1A1
SCHEMBL18338812 0.88 CA3 (0.54) KDM4EMAPK1HIF1APRMT1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841496-B1 RUBBER COMPOSITIONS ALLNEX GERMANY GMBH (DE) 2022-10-26 EP claimed
EP-4429644-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM ModernaTX, Inc. (US) 2024-09-18 EP disclosed
CN-116348147-A Compositions for delivery of payload molecules to airway epithelium 摩登纳特斯有限公司 2023-06-27 CN disclosed
WO-2023086465-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM MODERNATX, INC. (US) 2023-05-19 WO disclosed
CN-114230950-A Semiconductor equipment sealing element and preparation method thereof 上海芯密科技有限公司 2022-03-25 CN disclosed
CN-114196146-A Preparation method and application of semiconductor sealing element 上海芯密科技有限公司 2022-03-18 CN disclosed
CN-113166122-A Small molecule inhibitors of galectin-3 百时美施贵宝公司 2021-07-23 CN disclosed
US-20200361910-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2020-11-19 US disclosed
WO-2019030197-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2019-02-14 WO disclosed
US-5484457-A Continuous production of surface dyeings on cellulose fiber textile materials BASF AKTIENGESELLSCHAFT (DE) 1996-01-16 US disclosed
US-5234626-A Polyethers crosslinked by a urea or carbamate; crude oils; residual oils; oil fields BASF AKTIENGESELLSCHAFT (DE) 1993-08-10 US disclosed
US-5224963-A Improving perspiration fastness BASF AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
US-5015754-A Cationic polyethers for fixing reative and direct dyes used for dyeing and printing cellulose textiles; washfastness BASF AKTIENGESELLSCHAFT (DE) 1991-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361910-A1 PROCESS TO PREPARE PROPYLENE AMINES AND PROPYLENE AMINE DERIVATIVES HRH3, HRH4, HRH1 KDM4E 3714/4885MAPK1 327/4885HIF1A 678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.