Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412565 | 0.87 | ALDH1A1 (0.84) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL3408380 | 0.78 | ALDH1A1 (1.00) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL3410106 | 0.78 | GAA (0.81) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL3409860 | 0.77 | GAA (0.70) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL14671911 | 0.77 | GAA (0.70) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL14886133 | 0.77 | MAPT (0.72) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL3412404 | 0.74 | ALDH1A1 (0.74) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL22910535 | 0.73 | SLC6A4 (0.49) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL11009626 | 0.71 | ALDH1A1 (0.68) | GAAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL25380870 | 0.71 | MEN1 (0.54) | GAAALDH1A1KDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130707-A9 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011130707-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2011-10-20 | — | — | WO | disclosed |