Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | CRHBP | P24387 | 1/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412565 | 0.92 | ALDH1A1 (0.84) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL3410106 | 0.88 | GAA (0.81) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL14886133 | 0.84 | MAPT (0.72) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL3404174 | 0.82 | ALDH1A1 (0.70) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL11009626 | 0.81 | ALDH1A1 (0.68) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL3420575 | 0.78 | GAA (0.79) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL11010923 | 0.77 | MAPT (0.63) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL5542214 | 0.77 | KDM4E (0.62) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL7000552 | 0.76 | KDM4E (0.69) | ALDH1A1GAAKDM4EMAPK1TSHR | |
| SCHEMBL14542280 | 0.74 | ABCB1 (0.62) | ALDH1A1GAAKDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130101684-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | CHROMOCELL CORPORATION (US) | 2013-04-25 | — | — | US | disclosed |
| WO-2011130707-A9 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011130707-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR REDUCING OR ELIMINATING BITTER TASTE | CHROMOCELL CORPORATION (US) | 2011-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130101684-A1 | Compounds, Compositions, And Methods For Reducing Or Eliminating Bitter Taste | TAS2R5, TAS2R20, TAS2R10 | ALDH1A1 1771/4885GAA 374/4885KDM4E 2256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.