Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3420976

NCCOCCN1C(=O)C=CC1=O.O=C(O)C(F)(F)F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 4/20 0.56
▸ PTGS1 P23219 4/20 0.38
▸ PTGS2 P35354 4/20 0.38
▸ FAAH O00519 2/20 0.36
▸ DRD2 P14416 1/20 0.36
▸ DRD3 P35462 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ HSP90AA1 P07900 1/20 0.35
▸ TLR9 Q9NR96 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ XBP1 P17861 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ RECQL P46063 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL18261569 0.98 MGLL (0.59) MGLLPTGS1PTGS2FAAHDRD2
SCHEMBL7943421 0.85 MGLL (0.76) MGLLPTGS1PTGS2FAAHALDH1A1
Trifluoroacetic Acid SCHEMBL4967709 0.84 MGLL (0.47) MGLLPTGS1PTGS2FAAHDRD2
Trifluoroacetic Acid SCHEMBL247137 0.84 PTGS1 (0.44) MGLLPTGS1PTGS2FAAHDRD2
SCHEMBL24797392 0.84 MGLL (0.80) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL13755287 0.84 MGLL (0.80) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL22311910 0.84 MGLL (0.80) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL22311931 0.84 MGLL (0.80) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL16006807 0.84 MGLL (0.80) MGLLPTGS1PTGS2FAAHALDH1A1
SCHEMBL20026448 0.84 MGLL (0.80) MGLLPTGS1PTGS2FAAHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12479933-B2 Crosslinked alginic acid structure MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2025-11-25 — — US disclosed
EP-3778653-B1 NOVEL REACTIVE ALGINIC ACID DERIVATIVES MOCHIDA PHARM CO LTD (JP) 2025-07-09 — — EP disclosed
CN-114521199-B Cross-linked alginic acid structure 持田制药株式会社 2025-05-30 — — CN disclosed
US-20220396643-A1 NOVEL CROSSLINKED ALGINIC ACID STRUCTURE MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-12-15 — — US disclosed
US-11472892-B2 Reactive alginic acid derivatives MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 — — US disclosed
EP-4035735-A1 NOVEL CROSSLINKED ALGINIC ACID STRUCTURE Mochida Pharmaceutical Co., Ltd. (JP) 2022-08-03 — — EP disclosed
CN-111868096-B Reactive alginic acid derivatives 持田制药株式会社 2022-06-17 — — CN disclosed
CN-114521199-A Novel cross-linked alginic acid structure 持田制药株式会社 2022-05-20 — — CN disclosed
US-11141489-B2 Conjugates comprising an GLP-1/Glucagon dual agonist, a linker and hyaluronic acid SANOFI (FR) 2021-10-12 — — US disclosed
EP-3778653-A1 NOVEL REACTIVE ALGINIC ACID DERIVATIVES Mochida Pharmaceutical Co., Ltd. (JP) 2021-02-17 — — EP disclosed
US-9352049-B2 Ligand-therapeutic agent conjugates, silicon-based linkers, and methods for making and using them ALBANY MOLECULAR RESEARCH, INC. (US) 2016-05-31 — — US disclosed
EP-2968599-A1 LIGAND-THERAPEUTIC AGENT CONJUGATES AND SILICON-BASED LINKERS Albany Molecular Research, Inc. (US) 2016-01-20 — — EP disclosed
US-20140322247-A1 CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF NOVARTIS AG (CH) 2014-10-30 — — US disclosed
WO-2014160305-A1 LIGAND-THERAPEUTIC AGENT CONJUGATES AND SILICON-BASED LINKERS ALBANY MOLECULAR RESEARCH, INC. (US) 2014-10-02 — — WO disclosed
US-20140274951-A1 LIGAND-THERAPEUTIC AGENT CONJUGATES, SILICON-BASED LINKERS, AND METHODS FOR MAKING AND USING THEM ALBANY MOLECULAR RESEARCH, INC. (US) 2014-09-18 — — US disclosed
US-20140186875-A1 NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSIS MONTANA STATE UNIVERSITY (US) 2014-07-03 — — US disclosed
US-20100252433-A1 NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES NATIONAL SCIENCE FOUNDATION 2010-10-07 — — US disclosed
EP-2164997-A2 NOVEL OPTICAL LABELING MOLECULES IN PROTEOMICS AND OTHER BIOLOGICAL ANALYSES Montana State University (US) 2010-03-24 — — EP disclosed
WO-2009005871-A2 NOVEL OPTICAL LABELING MOLECULES IN PROTEOMICS AND OTHER BIOLOGICAL ANALYSES MONTANA STATE UNIVERSITY (US) 2009-01-08 — — WO disclosed
US-5053503-A For joining antibodies and metallic radionuclides CENTOCOR (US) 1991-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100252433-A1 NOVEL OPTICAL LABELING MOLECULES FOR PROTEOMICS AND OTHER BIOLOGICAL ANALYSES PTMS, CHAMP1, RAB5IF MGLL 2648/4885PTGS1 2733/4885PTGS2 2989/4885
US-20140274951-A1 LIGAND-THERAPEUTIC AGENT CONJUGATES, SILICON-BASED LINKERS, AND METHODS FOR MAKING AND USING THEM CD44, CD47, SELPLG MGLL 4065/4885PTGS1 4025/4885PTGS2 4195/4885
US-11141489-B2 Conjugates comprising an GLP-1/Glucagon dual agonist, a linker and hyaluronic acid GLP1R, GIPR, GCGR MGLL 413/4885PTGS1 1526/4885PTGS2 2286/4885
US-20140322247-A1 CELL PROLIFERATION INHIBITORS AND CONJUGATES THEREOF MKI67, CCNI, PA2G4 MGLL 4070/4885PTGS1 3295/4885PTGS2 3774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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