Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2385691 | 0.87 | PTGS1 (0.50) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL18261569 | 0.86 | MGLL (0.59) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL16970580 | 0.85 | MGLL (0.53) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL3420976 | 0.84 | MGLL (0.56) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6991874 | 0.84 | PTGS1 (0.56) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL4971470 | 0.84 | PTGS1 (0.56) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| Trifluoroacetic Acid SCHEMBL6442497 | 0.81 | MGLL (0.42) | MGLLPTGS1PTGS2FAAHALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL247137 | 0.80 | PTGS1 (0.44) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| SCHEMBL10072540 | 0.78 | MGLL (0.75) | MGLLPTGS1PTGS2FAAHHSP90AA1 | |
| SCHEMBL15503283 | 0.78 | MGLL (0.75) | MGLLPTGS1PTGS2FAAHHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585791-B1 | HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONJUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS | BAYER SCHERING PHARMA AG (DE) | 2008-09-24 | — | — | EP | disclosed |
| CN-101022835-A | Antibody conjugated cyanine dyes for the diagnosis of micrometastasis | BAYER SCHERING PHARMA AG (DE) | 2007-08-22 | — | — | CN | disclosed |
| EP-1816475-A1 | Use of cyanine dyes for the diagnosis of disease associated with angiogenesis | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1784226-A2 | CYANINE DYES CONJUGATED WITH ANTIBODIES FOR THE DIAGNOSIS OF MICROMETASTASIS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-05-16 | — | — | EP | disclosed |
| CN-1742057-A | Hydrophilic, thiol-reactive cyanine dyes and conjugates thereof with biomolecules for fluorescence diagnosis | SCHERING AG (DE) | 2006-03-01 | — | — | CN | disclosed |
| US-20060039863-A1 | Use of cyanine dyes for the diagnosis of disease associated with angiogenesis | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-02-23 | — | — | US | disclosed |
| WO-2006008179-A2 | CYANINE DYES CONJUGATED WITH ANTIBODIES FOR THE DIAGNOSIS OF MICROMETASTASIS | SCHERING AG (DE) | 2006-01-26 | — | — | WO | disclosed |
| EP-1619501-A1 | Use of cyanine dyes for the diagnosis of disease associated with angiogenesis | Schering AG (DE) | 2006-01-25 | — | — | EP | disclosed |
| EP-1585791-A1 | HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONJUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS | Schering AG (DE) | 2005-10-19 | — | — | EP | disclosed |
| US-20040260072-A1 | Hydrophilic, thiol-reactive cyanine dyes and conjugates thereof with biomolecules for fluorescence diagnosis | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2004-12-23 | — | — | US | disclosed |
| WO-2004065491-A1 | HYDROPHILIC, THIOL-REACTIVE CYANINE DYES AND CONJUGATES THEREOF WITH BIOMOLECULES FOR FLUORESCENCE DIAGNOSIS | SCHERING AG (DE) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040260072-A1 | Hydrophilic, thiol-reactive cyanine dyes and conjugates thereof with biomolecules for fluorescence diagnosis | TST, ABCG2, SPR | MGLL 4340/4885PTGS1 2569/4885PTGS2 2599/4885 |
| US-20060039863-A1 | Use of cyanine dyes for the diagnosis of disease associated with angiogenesis | MYADM, CD14, CD68 | MGLL 4848/4885PTGS1 3124/4885PTGS2 3402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.