Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.54 |
| ▸ | NQO2 | P16083 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 8/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ESRRG | P62508 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628787 | 1.00 | PTGS1 (0.54) | PTGS1NQO2PTGS2ESR1ESR2 | |
| SCHEMBL18634918 | 1.00 | PTGS1 (0.54) | PTGS1NQO2PTGS2ESR1ESR2 | |
| SCHEMBL11147182 | 0.84 | TSHR (0.43) | PTGS1NQO2PTGS2ESR1ESR2 | |
| SCHEMBL3149927 | 0.82 | CYP19A1 (0.41) | PTGS1NQO2PTGS2ESR1ESR2 | |
| SCHEMBL3149925 | 0.82 | CYP19A1 (0.41) | PTGS1NQO2PTGS2ESR1ESR2 | |
| SCHEMBL12572498 | 0.81 | ESR1 (0.52) | PTGS1NQO2PTGS2ESR1ESR2 | |
| SCHEMBL3442786 | 0.78 | KDM1A (0.39) | ESR1ESR2CYP3A4ESRRGALDH1A1 | |
| SCHEMBL3442788 | 0.78 | KDM1A (0.39) | ESR1ESR2CYP3A4ESRRGALDH1A1 | |
| SCHEMBL18699329 | 0.76 | ESR1 (0.64) | PTGS1NQO2PTGS2ESR1ESR2 | |
| SCHEMBL2989490 | 0.76 | KDM1A (0.38) | ESR1ESR2CYP3A4ESRRGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002887-B1 | A LINEAR TRIMER OF P-ISOPROPENYL PHENOL, A PROCESS FOR THE PREPARATION OF THE TRIMER, EPOXY RESINS CURED USING THE TRIMER AND AN EPOXY DERIVATIVE OF THE TRIMER | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1981-11-25 | — | — | EP | claimed |
| US-4201877-A | ACID CATALYST, SOLVENT | MITSUI TOATSU CHEMICALS INC. (JP) | 1980-05-06 | — | — | US | claimed |
| EP-0002887-A1 | A linear trimer of p-isopropenyl phenol, a process for the preparation of the trimer, epoxy resins cured using the trimer and an epoxy derivative of the trimer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-07-11 | — | — | EP | claimed |
| JP-62010050-A | — | — | None | — | — | JP | disclosed |
| JP-9059366-A | — | — | None | — | — | JP | disclosed |
| US-10155709-B2 | Sythesis of bisphenols | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-12-18 | — | — | US | disclosed |
| US-20170174598-A1 | SYTHESIS OF BISPHENOLS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-22 | — | — | US | disclosed |
| EP-3169658-A1 | SYNTHESIS OF BISPHENOLS | SABIC Global Technologies B.V. (NL) | 2017-05-24 | — | — | EP | disclosed |
| US-9255053-B2 | Treatment of bisphenol-A residue streams | BADGER LICENSING LLC (US) | 2016-02-09 | — | — | US | disclosed |
| WO-2016009362-A1 | SYNTHESIS OF BISPHENOLS | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-21 | — | — | WO | disclosed |
| EP-2718252-B1 | TREATMENT OF BISPHENOL-A RESIDUE STREAMS | BADGER LICENSING LLC (US) | 2015-04-22 | — | — | EP | disclosed |
| US-4418220-A | Novel indene compound and novel process for producing indene compounds | MITSUI TOATSU CHEMICALS INC. (JP) | 1983-11-29 | — | — | US | disclosed |
| US-4397864-A | LOW TOXICITY | MITSUITOATSU CHEMICALS INC. (JP) | 1983-08-09 | — | — | US | disclosed |
| US-4374272-A | Process for preparing 2-(4'-hydroxyaryl)-2-(4'-aminoaryl)-propanes | MITSUI TOATSU CHEMICALS, INC. (JP) | 1983-02-15 | — | — | US | disclosed |
| US-4366328-A | HEAT DECOMPOSITION OF A 1,1,3-TRIMETHYL, 3-HYDROXYPHENYL, HYDROXYINDANE USING AN ACID OR BASIC CATALYST; DEARYLATION; AROMATIZATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1982-12-28 | — | — | US | disclosed |
| US-4334106-A | CYLIZATION | THE UPJOHN COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0002887-B1 | A LINEAR TRIMER OF P-ISOPROPENYL PHENOL, A PROCESS FOR THE PREPARATION OF THE TRIMER, EPOXY RESINS CURED USING THE TRIMER AND AN EPOXY DERIVATIVE OF THE TRIMER | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1981-11-25 | — | — | EP | disclosed |
| US-4242528-A | THERMAL DECOMPOSITION OF OLIGOMERS | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4201877-A | ACID CATALYST, SOLVENT | MITSUI TOATSU CHEMICALS INC. (JP) | 1980-05-06 | — | — | US | disclosed |
| EP-0002887-A1 | A linear trimer of p-isopropenyl phenol, a process for the preparation of the trimer, epoxy resins cured using the trimer and an epoxy derivative of the trimer | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174598-A1 | SYTHESIS OF BISPHENOLS | TET1, BCHE, ESR1 | PTGS1 1013/4885NQO2 656/4885PTGS2 1157/4885 |
| US-10155709-B2 | Sythesis of bisphenols | TET1, BCHE, ESR1 | PTGS1 1013/4885NQO2 656/4885PTGS2 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.