Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 6/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 3/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.31 |
| ▸ | PPARG | P37231 | 6/20 | 0.31 |
| ▸ | PPARD | Q03181 | 6/20 | 0.31 |
| ▸ | PPARA | Q07869 | 6/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TLR2 | O60603 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3417251 | 0.77 | APEX1 (0.41) | APEX1TSHRLMNASLC22A6AKR1B1 | |
| SCHEMBL3415399 | 0.75 | GRM4 (0.35) | LMNANFKB1PMP22ALDH1A1TDP1 | |
| SCHEMBL11330927 | 0.75 | APEX1 (0.68) | APEX1TSHRLMNASLC22A6AKR1B1 | |
| SCHEMBL6125451 | 0.70 | — | — | |
| SCHEMBL9084614 | 0.70 | APEX1 (0.54) | APEX1TSHRLMNASLC22A6AKR1B1 | |
| SCHEMBL9883954 | 0.69 | APEX1 (0.52) | APEX1TSHRLMNASLC22A6AKR1B1 | |
| SCHEMBL2675603 | 0.69 | APEX1 (0.65) | APEX1TSHRLMNASLC22A6AKR1B1 | |
| SCHEMBL28125631 | 0.68 | APEX1 (0.47) | APEX1TSHRLMNASLC22A6AKR1B1 | |
| SCHEMBL6577828 | 0.67 | GPR84 (0.64) | APEX1TSHRLMNASLC22A6AKR1B1 | |
| SCHEMBL6577850 | 0.67 | GPR84 (0.64) | APEX1TSHRLMNASLC22A6AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100272783-A1 | Methods of Treating Infections of the Nail | NOVABAY PHARMACEUTICALS, INC. | 2010-10-28 | — | — | US | claimed |
| WO-2010124237-A1 | METHODS OF TREATING INFECTIONS OF THE NAIL | NOVABAY PHARMACEUTICALS INC. (US) | 2010-10-28 | — | — | WO | claimed |
| US-20100272783-A1 | Methods of Treating Infections of the Nail | NOVABAY PHARMACEUTICALS, INC. | 2010-10-28 | — | — | US | disclosed |
| WO-2010124237-A1 | METHODS OF TREATING INFECTIONS OF THE NAIL | NOVABAY PHARMACEUTICALS INC. (US) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100272783-A1 | Methods of Treating Infections of the Nail | POLR1C, TYR, NACA | APEX1 1332/4885NAALAD2 288/4885TSHR 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.