Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6202148 | 0.81 | ALDH1A1 (0.55) | ALDH1A1CYP2D6ALOX15 | |
| SCHEMBL28859286 | 0.72 | ALDH1A1 (0.30) | ALDH1A1CYP2D6ALOX15 | |
| SCHEMBL10707321 | 0.70 | — | — | |
| SCHEMBL28603548 | 0.70 | ALDH1A1 (0.35) | ALDH1A1CYP2D6ALOX15 | |
| Bicarbonate SCHEMBL27133673 | 0.69 | ALDH1A1 (0.35) | ALDH1A1ALOX15 | |
| Bicarbonate SCHEMBL28340725 | 0.69 | — | — | |
| SCHEMBL2494480 | 0.67 | — | — | |
| SCHEMBL2317872 | 0.67 | — | — | |
| SCHEMBL22115813 | 0.67 | — | — | |
| SCHEMBL2494482 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110526868-A | A kind of preparation method of celecoxib | WEIHAI DISU PHARMACEUTICAL CO LTD | 2019-12-03 | — | — | CN | disclosed |
| EP-2216414-B1 | Cell-free translation system | UNIV BAYREUTH (DE) | 2012-08-22 | — | — | EP | disclosed |
| EP-2216414-A1 | Cell-free translation system | Universität Bayreuth (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1848815-B1 | ESTERASES FOR MONITORING PROTEIN BIOSYNTHESIS IN VITRO | UNIV BAYREUTH (DE) | 2010-05-19 | — | — | EP | disclosed |
| US-20090258348-A1 | ESTERASES FOR MONITORING PROTEIN BIOSYNTHESIS IN VITRO | UNIVERSITÄT BAYREUTH (DE) | 2009-10-15 | — | — | US | disclosed |
| EP-1848815-A1 | ESTERASES FOR MONITORING PROTEIN BIOSYNTHESIS IN VITRO | Universität Bayreuth (DE) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006082059-A1 | ESTERASES FOR MONITORING PROTEIN BIOSYNTHESIS IN VITRO | UNIVERSITÄT BAYREUTH (DE) | 2006-08-10 | — | — | WO | disclosed |
| EP-0468457-B1 | Novel substituted piperidines and their use as inhibitors of cholesterol synthesis | MERRELL DOW PHARMA (US) | 1996-03-06 | — | — | EP | disclosed |
| US-5217979-A | Substituted alkyl piperidines | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-08 | — | — | US | disclosed |
| EP-0468457-A1 | Novel substituted piperidines and their use as inhibitors of cholesterol synthesis | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| EP-0420116-A2 | Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258348-A1 | ESTERASES FOR MONITORING PROTEIN BIOSYNTHESIS IN VITRO | RNGTT, ANPEP, DNPEP | ALDH1A1 1902/4885CYP2D6 1742/4885ALOX15 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.