Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | GNG2 | P59768 | 1/20 | 0.38 |
| ▸ | GNB1 | P62873 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398015 | 0.98 | PTPN11 (0.78) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL14111955 | 0.87 | PTPN11 (1.00) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL30439544 | 0.87 | PTPN11 (1.00) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL16285462 | 0.80 | MEN1 (0.66) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL4634262 | 0.80 | TDP1 (0.65) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL151728 | 0.79 | PTPN11 (0.80) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL410463 | 0.78 | TDP1 (0.67) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL29436705 | 0.77 | MEN1 (0.70) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL152384 | 0.77 | MEN1 (0.70) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL4011093 | 0.76 | CDK2 (0.61) | PTPN11ALDH1A1CYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8278219-B2 | Method for purifying chemical added with chelating agent | NOMURA MICRO SCIENCE CO., LTD. (JP) | 2012-10-02 | — | — | US | disclosed |
| US-20100078589-A1 | METHOD FOR PURIFYING CHEMICAL ADDED WITH CHELATING AGENT | NOMURA MICRO SCIENCE CO., LTD. | 2010-04-01 | — | — | US | disclosed |