Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | GNG2 | P59768 | 1/20 | 0.39 |
| ▸ | GNB1 | P62873 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422255 | 0.98 | PTPN11 (0.76) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL14111955 | 0.88 | PTPN11 (1.00) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL30439544 | 0.88 | PTPN11 (1.00) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL16285462 | 0.81 | MEN1 (0.66) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL151728 | 0.80 | PTPN11 (0.80) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL410463 | 0.79 | TDP1 (0.67) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL29436705 | 0.78 | MEN1 (0.70) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL152384 | 0.78 | MEN1 (0.70) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL4634262 | 0.78 | TDP1 (0.65) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL4011093 | 0.78 | CDK2 (0.61) | PTPN11TDP1ALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180038802-A1 | METHOD FOR OPTICALLY DETERMINING AT LEAST ONE ANALYTE IN A SAMPLE | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2018-02-08 | — | — | US | claimed |
| EP-2698627-B1 | Method for optical determination of at least one analyte in a sample | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2017-01-18 | — | — | EP | claimed |
| US-20150219564-A1 | METHOD FOR OPTICALLY DETERMINING AT LEAST ONE ANALYTE IN A SAMPLE | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2015-08-06 | — | — | US | claimed |
| US-20130177485-A1 | DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY | MOMTEC LIFE LTD OF YAZMOT HAEMEK (IL) | 2013-07-11 | — | — | US | claimed |
| EP-2198299-A2 | A DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY | Mullerad, Jacob (IL) | 2010-06-23 | — | — | EP | claimed |
| WO-2009050711-A2 | A DIAGNOSTIC DEVICE FOR IDENTIFYING RUPTURE OF MEMBRANE DURING PREGNANCY | MULLERAD JACOB (IL) | 2009-04-23 | — | — | WO | claimed |
| US-4548907-A | Fluorescent fluid determination method and apparatus | ALLIED CORPORATION (US) | 1985-10-22 | — | — | US | claimed |
| EP-0137157-A2 | Fluid analysis technology using fluorescence type sensors | Fisher Scientific Company (US) | 1985-04-17 | — | — | EP | claimed |
| CN-112218577-A | Apparatus and method for tissue and cell staining | ESSENLIX公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-109791157-A | MEASUREMENT OF PROTEIN EXPRESSION USING REAGENTS WITH BARCODED OLIGONUCLEOTIDE SEQUENCES | 赛卢拉研究公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105101804-B | The selective depression of C4-PEP carboxylase | 杜塞尔多夫海因里希·海涅大学 | 2019-02-12 | — | — | CN | disclosed |
| US-10188107-B2 | Selective inhibition of C4-PEP carboxylases | HEINRICH HEINE UNIVERSITAT DUSSELDORF (DE) | 2019-01-29 | — | — | US | disclosed |
| CN-108474760-A | Target modification for tracking and detecting | 双孔人公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108368642-A | Method and system for providing labeled biomolecule | 贝克顿·迪金森公司 | 2018-08-03 | — | — | CN | disclosed |
| US-20020013427-A1 | Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers | KANEKA CORPORATION (JP) | 2002-01-31 | — | — | US | disclosed |
| EP-1146062-A1 | Method of producing crosslinkable silyl group-containing polyoxyalkylene polymers | Kaneka Corporation (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5790627-A | Method and apparatus for observing a specimen using an X-ray microscope | RESEARCH DEVELOPMENT CORP. (JP) | 1998-08-04 | — | — | US | disclosed |
| US-4548907-A | Fluorescent fluid determination method and apparatus | ALLIED CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0137157-A2 | Fluid analysis technology using fluorescence type sensors | Fisher Scientific Company (US) | 1985-04-17 | — | — | EP | disclosed |
| US-4361842-A | INK JET | CANON KABUSHIKI KAISHA (JP) | 1982-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10188107-B2 | Selective inhibition of C4-PEP carboxylases | PC, CPS1, ME1 | PTPN11 2118/4885TDP1 4442/4885ALDH1A1 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.