Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CPA1 | P15085 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL517277 | 1.00 | — | — | |
| Isopropylamine SCHEMBL8341815 | 0.90 | — | — | |
| Nitric Acid SCHEMBL3772020 | 0.86 | — | — | |
| Isopropyl Alcohol SCHEMBL10586828 | 0.86 | CA5A (0.61) | CA5ACA5BLMNAALDH1A1TP53 | |
| Isopropyl Alcohol SCHEMBL5903500 | 0.86 | — | — | |
| Nitric Acid SCHEMBL7573949 | 0.83 | CA5A (0.57) | CA5ACA5BLMNAALDH1A1TP53 | |
| Isopropyl Alcohol SCHEMBL2464934 | 0.80 | CA5A (0.53) | CA5ACA5BLMNAALDH1A1TP53 | |
| Nitric Acid SCHEMBL8208078 | 0.79 | CA5A (0.44) | CA5ACA5B | |
| Alanine SCHEMBL2513591 | 0.79 | CA5A (0.44) | CA5ACA5BALDH1A1SLC7A5TP53 | |
| Nitric Acid SCHEMBL2734749 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009063-A2 | PREMIXED LIQUID MONOPROPELLANT SOLUTIONS AND MIXTURES | ATLANTIC RESEARCH CORPORATION (US) | 2001-02-08 | — | — | WO | claimed |
| US-8618477-B2 | Method and apparatus for chemical and biological sample separation | EXCELLIMS CORPORATION (US) | 2013-12-31 | — | — | US | disclosed |
| US-20120305761-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | EXCELLIMS CORPORATION (US) | 2012-12-06 | — | — | US | disclosed |
| US-8242442-B2 | Method and apparatus for chemical and biological sample separation | EXCELLIMS CORPORATION (US) | 2012-08-14 | — | — | US | disclosed |
| US-20100127166-A1 | METHOD AND APPARATUS FOR CHEMICAL AND BIOLOGICAL SAMPLE SEPARATION | EXCELLIMS CORPORATION (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2001009063-A3 | PREMIXED LIQUID MONOPROPELLANT SOLUTIONS AND MIXTURES | ATLANTIC RES CORP (US) | 2008-03-06 | — | — | WO | disclosed |
| US-6984273-B1 | nondetonable mixtures consisting of oxidizers and fuels; nontoxic, low detonation sensitivity, environmentally friendly; perform effectively and provide maximum throttle control | AEROJET-GENERAL CORPORATION (US) | 2006-01-10 | — | — | US | disclosed |
| US-6984273-B1 | nondetonable mixtures consisting of oxidizers and fuels; nontoxic, low detonation sensitivity, environmentally friendly; perform effectively and provide maximum throttle control | AEROJET-GENERAL CORPORATION (US) | 2006-01-10 | — | — | US | disclosed |
| WO-2001009063-A2 | PREMIXED LIQUID MONOPROPELLANT SOLUTIONS AND MIXTURES | ATLANTIC RESEARCH CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |
| WO-2001009063-A2 | PREMIXED LIQUID MONOPROPELLANT SOLUTIONS AND MIXTURES | ATLANTIC RESEARCH CORPORATION (US) | 2001-02-08 | — | — | WO | disclosed |
| US-4780560-A | Nitrate derivatives and vasodilators containing the same | TERUMO CORPORATION (JP) | 1988-10-25 | — | — | US | disclosed |