Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Alanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 3/20 | 0.33 |
| ▸ | GABRD | O14764 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL2513658 | 1.00 | CA5A (0.44) | CA5ACA5BSLC7A5CPA1TP53 | |
| Alanine SCHEMBL2513661 | 1.00 | CA5A (0.44) | CA5ACA5BSLC7A5CPA1TP53 | |
| Alanine SCHEMBL2515144 | 1.00 | CA5A (0.44) | CA5ACA5BSLC7A5CPA1TP53 | |
| Alanine SCHEMBL2515145 | 1.00 | CA5A (0.44) | CA5ACA5BSLC7A5CPA1TP53 | |
| Alanine SCHEMBL2513592 | 1.00 | CA5A (0.44) | CA5ACA5BSLC7A5CPA1TP53 | |
| Alanine SCHEMBL31263680 | 0.89 | SLC7A5 (0.43) | SLC7A5CPA1TP53NOS1SLC1A3 | |
| Alanine SCHEMBL28244919 | 0.89 | SLC7A5 (0.43) | SLC7A5CPA1TP53NOS1SLC1A3 | |
| Nitric Acid SCHEMBL28716022 | 0.82 | CA5A (0.50) | CA5ACA5BSLC7A5CPA1TP53 | |
| Valine SCHEMBL1487681 | 0.82 | SLC7A5 (0.71) | CA5ACA5BSLC7A5CPA1TP53 | |
| Valine SCHEMBL15641609 | 0.82 | SLC7A5 (0.71) | CA5ACA5BSLC7A5CPA1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612370-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-04-28 | — | — | US | disclosed |
| US-12577210-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-03-17 | — | — | US | disclosed |
| US-12577209-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-03-17 | — | — | US | disclosed |
| US-12540119-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-02-03 | — | — | US | disclosed |
| US-12522568-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2026-01-13 | — | — | US | disclosed |
| US-12473261-B2 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2025-11-18 | — | — | US | disclosed |
| US-12448357-B1 | Amino acid compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2025-10-21 | — | — | US | disclosed |
| US-20250171406-A1 | AMINO ACID COMPOSITIONS | THERMOLIFE INTERNATIONAL, LLC | 2025-05-29 | — | — | US | disclosed |
| US-20250163001-A1 | AMINO ACID COMPOSITIONS | THERMOLIFE INTERNATIONAL, LLC | 2025-05-22 | — | — | US | disclosed |
| US-20250162996-A1 | AMINO ACID COMPOSITIONS | THERMOLIFE INTERNATIONAL, LLC | 2025-05-22 | — | — | US | disclosed |
| US-8344014-B2 | — | — | 2013-01-01 | — | — | US | disclosed |
| US-20120220642-A1 | Amino Acid Compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2012-08-30 | — | — | US | disclosed |
| US-20120220643-A1 | Amino Acid Compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2012-08-30 | — | — | US | disclosed |
| US-8183288-B2 | Amino acid compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2012-05-22 | — | — | US | disclosed |
| US-8178572-B2 | Amino acid compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110313043-A1 | Amino Acid Compositions | THERMOLIFE INTERNATIONAL, LLC (US) | 2011-12-22 | — | — | US | disclosed |
| US-8034836-B2 | Amino acid compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2011-10-11 | — | — | US | disclosed |
| US-7777074-B2 | Amino acid compounds | THERMOLIFE INTERNATIONAL, LLC (US) | 2010-08-17 | — | — | US | disclosed |
| US-20090105328-A1 | Amino Acid Compounds | THERMOLIFE INTERNATIONAL, LLC | 2009-04-23 | — | — | US | disclosed |
| US-20090076110-A1 | Amino Acid Compounds | THERMOLIFE INTERNATIONAL, LLC | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473261-B2 | Amino acid compositions | ASNS, GLUL, ARGLU1 | CA5A 1122/4885CA5B 1036/4885SLC7A5 13/4885 |
| US-20120220643-A1 | Amino Acid Compounds | AADAT, OAT, SLC1A5 | CA5A 285/4885CA5B 265/4885SLC7A5 8/4885 |
| US-20250162996-A1 | AMINO ACID COMPOSITIONS | ASNS, SLC1A5, BCAT2 | CA5A 1227/4885CA5B 1391/4885SLC7A5 8/4885 |
| US-12612370-B2 | Amino acid compositions | TNNT2, NPR1, NOS2 | CA5A 3426/4885CA5B 3076/4885SLC7A5 51/4885 |
| US-12448357-B1 | Amino acid compositions | SLC6A15, SLC1A5, SLC6A19 | CA5A 1548/4885CA5B 1512/4885SLC7A5 13/4885 |
| US-12540119-B2 | Amino acid compositions | NOS2, NOS1, NOS3 | CA5A 2081/4885CA5B 2326/4885SLC7A5 26/4885 |
| US-20090076110-A1 | Amino Acid Compounds | OAT, ARGLU1, ASNS | CA5A 1091/4885CA5B 1192/4885SLC7A5 46/4885 |
| US-12577209-B2 | Amino acid compositions | ARG1, NOS1, NOS2 | CA5A 2757/4885CA5B 2763/4885SLC7A5 27/4885 |
| US-20090105328-A1 | Amino Acid Compounds | DNPEP, AADAT, ASNS | CA5A 1326/4885CA5B 1200/4885SLC7A5 27/4885 |
| US-20250171406-A1 | AMINO ACID COMPOSITIONS | ASNS, GLUL, ARGLU1 | CA5A 1190/4885CA5B 1124/4885SLC7A5 14/4885 |
| US-12577210-B2 | Amino acid compositions | NPR1, SLC1A5, SLC6A15 | CA5A 2318/4885CA5B 2286/4885SLC7A5 14/4885 |
| US-20110313043-A1 | Amino Acid Compositions | ARGLU1, AADAT, MUSK | CA5A 1048/4885CA5B 1336/4885SLC7A5 31/4885 |
| US-20120220642-A1 | Amino Acid Compounds | AADAT, SLC10A2, SLC6A12 | CA5A 509/4885CA5B 451/4885SLC7A5 9/4885 |
| US-20250163001-A1 | AMINO ACID COMPOSITIONS | ASNS, GLUL, ARGLU1 | CA5A 1122/4885CA5B 1036/4885SLC7A5 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.