Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29778859 | 0.86 | CA1 (0.42) | ALDH1A1CYP3A4MAPK1MAPTRECQL | |
| SCHEMBL21603366 | 0.86 | FFAR4 (0.36) | ALDH1A1CYP3A4MAPK1MAPTRECQL | |
| SCHEMBL19643366 | 0.86 | CA1 (0.42) | ALDH1A1CYP3A4MAPK1MAPTRECQL | |
| Hydrochloric Acid SCHEMBL23531668 | 0.85 | POLB (0.35) | ALDH1A1CYP3A4MAPK1MAPTRECQL | |
| SCHEMBL15955640 | 0.85 | SCN9A (0.41) | ALDH1A1CYP3A4MAPK1MAPTRECQL | |
| SCHEMBL11284401 | 0.84 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CA1CA2CA9 | |
| SCHEMBL21603363 | 0.82 | MAPT (0.34) | ALDH1A1MAPK1MAPTRECQLL3MBTL1 | |
| SCHEMBL7928085 | 0.81 | ALDH1A1 (0.39) | ALDH1A1CYP3A4MAPK1MAPTRECQL | |
| SCHEMBL3155014 | 0.80 | AKR1C2 (0.49) | ALDH1A1MAPTGAACYP2C9SCN5A | |
| SCHEMBL21603493 | 0.79 | AKR1C2 (0.33) | ALDH1A1MAPK1MAPTRECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100434-A1 | HALOGEN CONTAINING EPOXY COMPOSITIONS AND THEIR PREPARATION | UNIVERSITY OF NORTH TEXAS (US) | 2005-10-27 | — | — | WO | claimed |
| US-20050228080-A1 | Halogen containing epoxy compositions and their preparation | UNIVERSITY OF NORTH TEXAS (US) | 2005-10-13 | — | — | US | claimed |
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| US-20230099293-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-03-30 | — | — | US | disclosed |
| EP-4077323-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2022-10-26 | — | — | EP | disclosed |
| CN-114867725-A | OGA inhibitor compounds | 詹森药业有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111285850-B | Isoindoline compounds, preparation method thereof, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2022-04-22 | — | — | CN | disclosed |
| US-20220041578-A1 | ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2022-02-10 | — | — | US | disclosed |
| EP-3896062-A1 | ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-10-20 | — | — | EP | disclosed |
| WO-2021123294-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| WO-2020114482-A1 | ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND | 中国科学院上海药物研究所 | 2020-06-11 | — | — | WO | disclosed |
| EP-0579280-A1 | Pesticidal method using N-phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1994-01-19 | — | — | EP | disclosed |
| US-5232940-A | Controlling insects, plant nematodes, helminths, protozoa | BASF AGRO B.V., ARNHEM (NL), WADENSWIL-BRANCH (CH) | 1993-08-03 | — | — | US | disclosed |
| US-5206257-A | Controlling plant nematodes, helminth, protozoa | MAY & BAKER LIMITED (GB) | 1993-04-27 | — | — | US | disclosed |
| US-5187185-A | Pesticidal 1-arylpyrroles | RHONE-POULENC AG COMPANY (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0372982-A2 | Pyrrole insecticides | RHONE-POULENC AGROCHIMIE (FR) | 1990-06-13 | — | — | EP | disclosed |
| EP-0295117-A1 | Derivatives of N-phenylpyrazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-12-14 | — | — | EP | disclosed |
| EP-0283173-A1 | Pesticidal method using 2-phenylimidazole derivatives | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1988-09-21 | — | — | EP | disclosed |
| EP-0234119-A1 | Pesticidal method using N-phenylpyrazoles | RHONE-POULENC AGROCHIMIE (FR) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987003781-A1 | PESTICIDAL METHOD USING N-PHENYLPYRAZOLES | MAY & BAKER LIMITED (GB) | 1987-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041578-A1 | ISOINDOLINE COMPOUND, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION OF ISOINDOLINE COMPOUND | CRBN, CUL4B, UBQLN1 | ALDH1A1 2041/4885CYP3A4 711/4885MAPK1 4316/4885 |
| US-20230099293-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | ALDH1A1 3839/4885CYP3A4 4278/4885MAPK1 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.