SCHEMBL3422913

SCHEMBL3422913

CCCOC(=O)C(O)=COc1ccccc1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.44
ALDH1A1 P00352 7/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
LMNA P02545 2/20 0.42
GAA P10253 1/20 0.42
KMT2A Q03164 2/20 0.41
PKM P14618 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
ADRB2 P07550 1/20 0.40
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778055 0.80 LMNA (0.49) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL1308171 0.80 LMNA (0.49) ALDH1A1SMN1; SMN2LMNAGAAKMT2A
SCHEMBL29000467 0.78 KDM4E (0.44) KDM4EALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL29071648 0.77 HTR6 (0.47) ALDH1A1SMN1; SMN2LMNAGAAL3MBTL1
SCHEMBL28373431 0.77 KMT2A (0.44) KDM4EALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL1834265 0.76 ELANE (0.51) KDM4EALDH1A1SMN1; SMN2LMNAKMT2A
SCHEMBL4202057 0.75 KDM4E (0.49) KDM4EALDH1A1SMN1; SMN2GAAKMT2A
SCHEMBL4193711 0.74 KDM4E (0.51) KDM4EALDH1A1SMN1; SMN2GAAKMT2A
SCHEMBL28219162 0.74 KDM4E (0.47) KDM4EALDH1A1SMN1; SMN2LMNAGAA
SCHEMBL4197864 0.74 FFAR4 (0.47) KDM4EALDH1A1SMN1; SMN2GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1650601-B1 Optical waveguide and manufacturing method thereof JSR CORP (JP) 2010-08-18 EP disclosed
US-7569335-B2 Photosensitive resin composition for optical waveguides, and optical waveguide and manufacturing method thereof JSR CORPORATION (JP) 2009-08-04 US disclosed
US-20080145016-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR OPTICAL WAVEGUIDES, AND OPTICAL WAVEGUIDE AND MANUFACTURING METHOD THEREOF JSR CORPORATION (JP) 2008-06-19 US disclosed
EP-1650601-A2 Photosensitive resin composition for optical waveguides, and optical waveguide and manufacturing method thereof JSR Corporation (JP) 2006-04-26 EP disclosed