Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL13736533 | 1.00 | RAD52 (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| Glycinebetaine SCHEMBL1245821 | 1.00 | RAD52 (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| Glycinebetaine SCHEMBL23528235 | 1.00 | RAD52 (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| SCHEMBL5269129 | 0.84 | NAAA (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| SCHEMBL593838 | 0.84 | NAAA (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| SCHEMBL6667795 | 0.84 | NAAA (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| SCHEMBL936782 | 0.84 | NAAA (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| SCHEMBL4674831 | 0.84 | NAAA (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| SCHEMBL22550911 | 0.84 | NAAA (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 | |
| SCHEMBL3674103 | 0.84 | NAAA (0.53) | RAD52NPSR1NAAAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | claimed |
| WO-2024143154-A1 | ANTIMICROBIAL PEPTIDE AND METHOD FOR PRODUCING SAME | 住友化学株式会社 | 2024-07-04 | — | — | WO | disclosed |
| US-20240101751-A1 | HOLLOW MICROBALLOON | TOKUYAMA CORPORATION (JP) | 2024-03-28 | — | — | US | disclosed |
| EP-4286439-A1 | HOLLOW MICROBALLOON | Tokuyama Corporation (JP) | 2023-12-06 | — | — | EP | disclosed |
| US-20230270655-A1 | PERSONAL CARE COMPOSITION AND USAGE METHOD THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-08-31 | — | — | US | disclosed |
| EP-4215246-A1 | PERSONAL CARE COMPOSITION WITH LOW SUBSTITUTED HYDROXYPROPYL CELLULOSE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-07-26 | — | — | EP | disclosed |
| US-20230203234-A1 | HOLLOW MICROBALLOONS | TOKUYAMA CORPORATION (JP) | 2023-06-29 | — | — | US | disclosed |
| US-20230151179-A1 | HOLLOW MICROBALLOONS FOR CMP POLISHING PAD | TOKUYAMA CORPORATION (JP) | 2023-05-18 | — | — | US | disclosed |
| EP-4039243-A1 | COMPOSITION FOR AEROSOL COSMETICS, AND AEROSOL COSMETICS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-08-10 | — | — | EP | disclosed |
| EP-3842178-A1 | BRAZING MATERIAL, BRAZING MEMBER, HEAT EXCHANGER, AND MANUFACTURING METHOD OF BRAZING MEMBER | Harima Chemicals, Incorporated (JP) | 2021-06-30 | — | — | EP | disclosed |
| EP-2642975-B1 | SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME | SHOWA DENKO KK (JP) | 2016-08-24 | — | — | EP | disclosed |
| US-9180079-B2 | Skin external preparation and method of producing same | SHOWA DENKO K.K. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-9012117-B2 | Toner, developer, toner container, process cartridge, image forming method, and image forming apparatus | RICOH COMPANY, LTD. (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8741520-B2 | Image forming toner, image forming apparatus, image forming method, and process cartridge | RICOH COMPANY, LTD. (JP) | 2014-06-03 | — | — | US | disclosed |
| US-20130287718-A1 | SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME | SHOWA DENKO K.K. (JP) | 2013-10-31 | — | — | US | disclosed |
| EP-2642975-A2 | SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME | Showa Denko K.K. (JP) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012153825-A2 | SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME | SHOWA DENKO K.K. (JP) | 2012-11-15 | — | — | WO | disclosed |
| US-20100316944-A1 | TONER, DEVELOPER, TONER CONTAINER, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
| WO-2010001770-A1 | IMAGE FORMING TONER, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2010-01-07 | — | — | WO | disclosed |
| EP-1857534-A1 | DETERGENT COMPOSITION | Ajinomoto Co., Inc. (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130287718-A1 | SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME | RBP4, RBP1, PROC | RAD52 1096/4885NPSR1 3093/4885NAAA 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.