Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946718 | 0.94 | SRC (0.44) | SRCHTR5AALOX12KDM4EALDH1A1 | |
| SCHEMBL1870062 | 0.88 | PARP10 (0.43) | SRCHTR5AALDH1A1MAPTPARP1 | |
| SCHEMBL10912802 | 0.77 | SRC (0.46) | SRCKDM4EALDH1A1MAPTPARP1 | |
| SCHEMBL15366916 | 0.77 | SRC (0.43) | SRCMAPTPARP1PARP10PARP11 | |
| SCHEMBL17969105 | 0.76 | SRC (0.49) | SRCKDM4EMAPTPARP1TSHR | |
| SCHEMBL1082367 | 0.76 | SRC (0.49) | SRCKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6359546 | 0.76 | SRC (0.53) | SRCKDM4EMAPTPARP1PARP10 | |
| SCHEMBL5759503 | 0.76 | SRC (0.49) | SRCHTR5AALOX12KDM4EALDH1A1 | |
| SCHEMBL3744568 | 0.76 | SRC (0.38) | SRCALOX12KDM4EALDH1A1HPGD | |
| SCHEMBL6796232 | 0.76 | SRC (0.49) | SRCKDM4EPARP10PARP11TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119931978-A | Application of monoamine oxidase as catalyst in preparation of quinoline nitrogen heterocyclic compound | 河北工业大学 | 2025-05-06 | — | — | CN | claimed |
| CN-119702019-A | Catalyst for catalyzing selective hydrogenation of quinoline and preparation method thereof | 湘潭大学 | 2025-03-28 | — | — | CN | claimed |
| CN-109529907-B | Nitrogen-doped carbon material supported cobalt catalyst, preparation method thereof and application thereof in catalytic oxidation of N-heterocyclic compound | 中南民族大学 | 2021-10-15 | — | — | CN | claimed |
| CN-109529907-A | A kind of nitrogen-doped carbon material load cobalt catalyst and preparation method thereof and the application in N- heterocyclic compound catalysis oxidation | 中南民族大学 | 2019-03-29 | — | — | CN | claimed |
| CN-107141252-A | A kind of method that hydrotalcite-like materials are catalyzed nitrogen-containing heterocycle compound oxidative dehydrogenation | 常州大学 | 2017-09-08 | — | — | CN | claimed |
| US-7101869-B2 | 2,4-diaminopyrimidine compounds useful as immunosuppressants | PFIZER INC. (US) | 2006-09-05 | — | — | US | claimed |
| EP-1242403-B1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS USFUL AS IMMUNOSUPPRESSANTS | PFIZER PROD INC (US) | 2006-01-04 | — | — | EP | claimed |
| US-20030191307-A1 | 2,4-Diaminopyrimidine compounds useful as immunosuppressants | BLUMENKOPF TODD A (US) | 2003-10-09 | — | — | US | claimed |
| EP-4580621-A2 | T-TYPE VOLTAGE-GATED CALCIUM CHANNEL POTENTIATORS | The Broad Institute, Inc. (US) | 2025-07-09 | — | — | EP | disclosed |
| CN-120091815-A | T-type voltage-gated calcium channel enhancer | 广泛研究所股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-119931978-A | Application of monoamine oxidase as catalyst in preparation of quinoline nitrogen heterocyclic compound | 河北工业大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-119702019-A | Catalyst for catalyzing selective hydrogenation of quinoline and preparation method thereof | 湘潭大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-115448888-B | Preparation method of phenazine compound | 华南理工大学 | 2024-03-12 | — | — | CN | disclosed |
| WO-2024050312-A2 | T-TYPE VOLTAGE-GATED CALCIUM CHANNEL POTENTIATORS | THE BROAD INSTITUTE, INC. (US) | 2024-03-07 | — | — | WO | disclosed |
| EP-1242403-A1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS USFUL AS IMMUNOSUPPRESSANTS | Pfizer Products Inc. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001040215-A1 | 2,4-DIAMINOPYRIMIDINE COMPOUNDS USFUL AS IMMUNOSUPPRESSANTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | disclosed |
| EP-0428351-B1 | Synthesis of quinoline and substituted quinoline copolymers | EXXON RESEARCH ENGINEERING CO (US) | 1994-12-21 | — | — | EP | disclosed |
| EP-0428351-A2 | Synthesis of quinoline and substituted quinoline copolymers | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0399278-A2 | Heterocyclic amidine derivatives | BASF Aktiengesellschaft (DE) | 1990-11-28 | — | — | EP | disclosed |
| EP-0173208-A1 | Tetrahydroquinolin-1-yl-carbonyl-imidazole derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191307-A1 | 2,4-Diaminopyrimidine compounds useful as immunosuppressants | CCR1, AOC1, NOD1 | SRC 3262/4885HTR5A 2812/4885ALOX12 1132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.