Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | DDO | Q99489 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3418597 | 0.82 | DAO (0.59) | DAOATMMEN1NPC1RAB9A | |
| SCHEMBL15690324 | 0.82 | GRIN2D (0.51) | DAODDOATMMEN1NPC1 | |
| SCHEMBL30716611 | 0.82 | DAO (0.59) | DAOATMMEN1NPC1RAB9A | |
| SCHEMBL8581497 | 0.81 | PARP1 (0.46) | DAODDOATMMEN1NPC1 | |
| SCHEMBL30667289 | 0.80 | DAO (0.71) | DAODDOMEN1KMT2AKDM4E | |
| SCHEMBL20247282 | 0.80 | DAO (0.71) | DAODDOMEN1KMT2AKDM4E | |
| SCHEMBL12969925 | 0.80 | ATM (0.64) | DAODDOATMMEN1NPC1 | |
| SCHEMBL7431309 | 0.78 | CYP1A2 (0.56) | ATMMEN1NPC1RAB9AKMT2A | |
| SCHEMBL31139816 | 0.76 | DAO (0.65) | DAODDOMEN1KMT2AKDM4E | |
| SCHEMBL3423807 | 0.76 | DAO (1.00) | DAODDOKDM4EMAPTFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |