Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.71 |
| ▸ | DDO | Q99489 | 4/20 | 0.71 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30667289 | 1.00 | DAO (0.71) | DAODDOBRD4ATAD2CYP1A2 | |
| SCHEMBL20940200 | 0.83 | DAO (0.65) | DAODDOBRD4ATAD2CYP1A2 | |
| SCHEMBL26551030 | 0.83 | BRD4 (0.53) | DAODDOBRD4ATAD2CYP1A2 | |
| SCHEMBL3423807 | 0.83 | DAO (1.00) | DAODDOBRD4CYP1A2TNKS2 | |
| SCHEMBL31139816 | 0.83 | DAO (0.65) | DAODDOBRD4CYP1A2TNKS2 | |
| SCHEMBL29471220 | 0.83 | BRD4 (0.53) | DAODDOBRD4ATAD2CYP1A2 | |
| SCHEMBL12970533 | 0.83 | DAO (0.65) | DAODDOBRD4ATAD2CYP1A2 | |
| SCHEMBL830278 | 0.80 | DAO (0.61) | DAODDOBRD4CYP1A2TNKS2 | |
| SCHEMBL3423473 | 0.80 | DAO (0.61) | DAODDOBRD4CYP1A2TNKS2 | |
| SCHEMBL12969925 | 0.80 | ATM (0.64) | DAODDOBRD4ATAD2TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3333157-B1 | VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS | HARBIN ZHENBAO PHARMACEUTICAL CO LTD (CN) | 2020-12-23 | — | — | EP | disclosed |
| EP-3333157-A1 | VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS | Harbin Zhenbao Pharmaceutical Co., Ltd. (CN) | 2018-06-13 | — | — | EP | disclosed |