SCHEMBL342380

SCHEMBL342380

O=[N+]([O-])c1n[nH]c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
GAA P10253 3/20 0.48
CYP3A4 P08684 2/20 0.48
PDPK1 O15530 1/20 0.48
MAPT P10636 3/20 0.47
HPGD P15428 2/20 0.47
NOS1 P29475 2/20 0.46
CYP1A2 P05177 2/20 0.46
ALDH1A1 P00352 4/20 0.46
IDO1 P14902 2/20 0.46
ALPL P05186 1/20 0.46
TTK P33981 1/20 0.46
MAPK10 P53779 1/20 0.46
STAT3 P40763 1/20 0.45
HIF1A Q16665 1/20 0.45
NPC1 O15118 1/20 0.43
TP53 P04637 1/20 0.43
RAB9A P51151 1/20 0.43
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30071547 1.00 KDM4E (0.48) KDM4EGAACYP3A4PDPK1MAPT
Hydrochloric Acid SCHEMBL28220934 0.98 KDM4E (0.47) KDM4EGAACYP3A4PDPK1MAPT
Carbamic Acid SCHEMBL1861901 0.90 KDM4E (0.45) KDM4EGAACYP3A4PDPK1MAPT
SCHEMBL8988307 0.85 MAPT (0.41) KDM4EGAACYP3A4PDPK1MAPT
SCHEMBL9493092 0.83 FGFR1 (0.46) KDM4EGAAPDPK1MAPTHPGD
SCHEMBL4056717 0.79 AR (0.54) KDM4EGAAMAPTALDH1A1MEN1
SCHEMBL921416 0.77 DAO (0.51) CYP3A4MAPTHPGDNOS1ALDH1A1
SCHEMBL30833662 0.77 DAO (0.51) CYP3A4MAPTHPGDNOS1ALDH1A1
SCHEMBL6556918 0.76 PIM1 (0.43) CYP3A4MAPTHPGDCYP1A2ALDH1A1
SCHEMBL29281238 0.75 PDPK1 (0.54) KDM4ECYP3A4PDPK1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2521 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578348-B2 Blood indicators of Alzheimer's disease THE INSTITUTE FOR ETHNOMEDICINE (US) 2026-03-17 US claimed
US-20250382671-A1 METHODS OF DETECTION AND ANALYSIS OF NUCLEIC ACID IN CIRCULATING BODILY FLUIDS Brain Chemistry Labs (US) 2025-12-18 US claimed
WO-2025243001-A1 COVALENT TAG UNIVERSITY OF DUNDEE (GB) 2025-11-27 WO claimed
EP-4287941-A1 BLOOD INDICATORS OF ALZHEIMER'S DISEASE The Institute For Ethnomedicine DBA Brain Chemistry Labs (US) 2023-12-13 EP claimed
EP-4069868-A2 METHODS OF DETECTION AND ANALYSIS OF NUCLEIC ACID IN NEURAL-DERIVED EXOSOMES The Institute For Ethnomedicine DBA Brain Chemistry Labs (US) 2022-10-12 EP claimed
US-20220252620-A1 BLOOD INDICATORS OF ALZHEIMER'S DISEASE The Institute for Ethnomedicine dba Brain Chemistry Labs 2022-08-11 US claimed
WO-2022168006-A1 BLOOD INDICATORS OF ALZHEIMER'S DISEASE The Institute for Ethnomedicine dba Brain Chemistry Labs (US) 2022-08-11 WO claimed
WO-2021113394-A2 METHODS OF DETECTION AND ANALYSIS OF NUCLEIC ACID IN NEURAL-DERIVED EXOSOMES The Institute for Ethnomedicine dba Brain Chemistry Labs (US) 2021-06-10 WO claimed
US-20210164051-A1 METHODS OF DETECTION AND ANALYSIS OF NUCLEIC ACID IN NEURAL-DERIVED EXOSOMES The Institute for Ethnomedicine dba Brain Chemistry Labs 2021-06-03 US claimed
CN-106399484-B Double-bubble fluorescent probe and application and kit thereof 中国人民解放军第三军医大学第一附属医院 2020-03-24 CN claimed
US-5272045-A Water soluble antifoggant for powder developer solutions SUN CHEMICAL CORPORATION (US) 1993-12-21 US claimed
EP-0448841-B1 PHOTOGRAPHIC MATERIALS CONTAINING ELECTRON ACCEPTING AGENTS AGFA-GEVAERT N.V. (BE) 1993-06-02 EP claimed
US-5198333-A Nitro-containing heterocyclic compoudns; positive or negative roomlight emulsions; graphic arts AGFA-GEVAERT, N.V. (BE) 1993-03-30 US claimed
EP-0448841-A1 Photographic materials containing electron accepting agents AGFA-GEVAERT N.V. (BE) 1991-10-02 EP claimed
US-4978603-A Developing an emulsion layer containing a rhodium salt and a preferential grain size using a dihydroxy developer, a sulfite and an indazole compound FUJI PHOTO FILM CO., LTD. (JP) 1990-12-18 US claimed
EP-0316864-A2 Silver halide photographic light-sensitive material and processing method KONICA CORPORATION (JP) 1989-05-24 EP claimed
EP-0060118-B1 STABLE PHOTOGRAPHIC DEVELOPING SOLUTION CONTAINING AN INDAZOLE ANTIFOGGANT AND A LIGNOSULFONATE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-02-13 EP claimed
EP-0060118-A1 Stable photographic developing solution containing an indazole antifoggant and a lignosulfonate EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-09-15 EP claimed
US-4323643-A HIGH CONTRAST USING UREIDO ARYLHYDRAZIDE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1982-04-06 US claimed
US-4323642-A Stable photographic developers containing an indazole antifoggant and a lignosulfonate EASTMAN KODAK COMPANY (US) 1982-04-06 US claimed