SCHEMBL9493092

SCHEMBL9493092

Clc1nc2ccccc2[nH]1.O=[N+]([O-])c1n[nH]c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 1/20 0.46
FLT1 P17948 1/20 0.46
MMP2 P08253 2/20 0.43
MMP9 P14780 2/20 0.43
MMP8 P22894 2/20 0.43
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
GAA P10253 1/20 0.41
PKM P14618 1/20 0.41
MAPT P10636 6/20 0.40
ALDH1A1 P00352 3/20 0.40
MMP13 P45452 1/20 0.40
ATM Q13315 1/20 0.40
LMNA P02545 3/20 0.40
HTT P42858 2/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
CCR6 P51684 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
NPC1 O15118 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL342380 0.83 KDM4E (0.48) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL30071547 0.83 KDM4E (0.48) KMT2AMEN1GAAMAPTALDH1A1
Hydrochloric Acid SCHEMBL28220934 0.81 KDM4E (0.47) KMT2AMEN1GAAMAPTALDH1A1
Carbamic Acid SCHEMBL1861901 0.75 KDM4E (0.45) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL277761 0.74 ALDH1A1 (0.60) FGFR1KMT2AMEN1GAAPKM
SCHEMBL29959355 0.74 ALDH1A1 (0.60) FGFR1KMT2AMEN1GAAPKM
SCHEMBL12003980 0.73 NPC1 (0.58) FGFR1KMT2AMEN1GAAPKM
Hydrochloric Acid SCHEMBL9698101 0.73 ALDH1A1 (0.58) FGFR1KMT2AMEN1GAAPKM
SCHEMBL8988307 0.70 MAPT (0.41) KMT2AMEN1GAAMAPTALDH1A1
SCHEMBL8874842 0.69 KMT2A (0.56) FGFR1MMP2MMP9MMP8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5206123-A Using alkaline developing solution in presence of a hydrazine; developing agents: dihydroxybenzene; 3-pyrazolidinone or aminophenol AGFA-GEVAERT, N.V. (BE) 1993-04-27 US disclosed