SCHEMBL3423875

SCHEMBL3423875

CC(C)(C)C1(c2ccccc2)C=CC(c2ccc(Br)cc2)=CC1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.34
KDM1A O60341 1/20 0.33
RCOR1 Q9UKL0 1/20 0.33
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
NPC1 O15118 1/20 0.30
NFKB1 P19838 1/20 0.30
RAB9A P51151 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30153644 0.90 GRIN2D (0.30)
SCHEMBL9750770 0.86 KIF11 (0.30)
SCHEMBL6563901 0.77 ALDH1A1 (0.38) ALDH1A1MAPK1KDM1ARCOR1NPC1
SCHEMBL21808461 0.72 ALDH1A1 (0.39) ALDH1A1MAPK1NPC1NFKB1RAB9A
Lithium SCHEMBL32659673 0.71
SCHEMBL30851342 0.71
SCHEMBL28386813 0.70 KDM1A (0.34) ALDH1A1MAPK1KDM1ARCOR1
SCHEMBL20530417 0.69 ALDH1A1 (0.33) ALDH1A1MAPK1KDM1ARCOR1MAPT
SCHEMBL29061574 0.67
SCHEMBL28402127 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9109081-B2 Method for producing aromatic polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-08-18 US disclosed
EP-1854833-B1 METHOD FOR PRODUCING AROMATIC POLYMER SUMITOMO CHEMICAL CO (JP) 2013-07-31 EP disclosed
US-20100144999-A1 METHOD FOR PRODUCING AROMATIC POLYMER SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2010-06-10 US disclosed
EP-1854833-A1 METHOD FOR PRODUCING AROMATIC POLYMER Sumitomo Chemical Company, Limited (JP) 2007-11-14 EP disclosed