Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393929 | 0.92 | MAPK1 (0.43) | PYGBL3MBTL1MAPTPOLBMAPK1 | |
| 1-Tuliposide A SCHEMBL30486311 | 0.88 | L3MBTL1 (0.43) | L3MBTL1MAPTPOLBSLC28A3GAA | |
| SCHEMBL15005813 | 0.85 | PYGB (0.49) | PYGBL3MBTL1MAPTKMT2APOLB | |
| SCHEMBL6950368 | 0.83 | L3MBTL1 (0.44) | PYGBL3MBTL1MAPTPOLBSLC28A3 | |
| SCHEMBL4468334 | 0.83 | L3MBTL1 (0.44) | PYGBL3MBTL1MAPTPOLBSLC28A3 | |
| SCHEMBL15128960 | 0.82 | L3MBTL1 (0.49) | PYGBL3MBTL1MAPTPOLBSLC28A3 | |
| SCHEMBL28341510 | 0.82 | L3MBTL1 (0.49) | PYGBL3MBTL1MAPTPOLBSLC28A3 | |
| SCHEMBL546798 | 0.82 | PYGB (0.51) | PYGBL3MBTL1MAPTSLC28A3GAA | |
| SCHEMBL8431126 | 0.82 | PYGB (0.51) | PYGBL3MBTL1MAPTSLC28A3GAA | |
| SCHEMBL17080327 | 0.82 | PYGB (0.51) | PYGBL3MBTL1MAPTSLC28A3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795176-B2 | Adsorbents for advanced glycation endproducts | KURUME UNIVERSITY (JP) | 2010-09-14 | — | — | US | disclosed |
| US-20090143226-A1 | Adsorbents for Advanced Glycation End products | KURUME UNIVERSITY | 2009-06-04 | — | — | US | disclosed |
| EP-1944034-A1 | ADSORBENT FOR ADVANCED GLYCATION ENDPRODUCTS | Kurume University (JP) | 2008-07-16 | — | — | EP | disclosed |