Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3424602 | 0.84 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL1939478 | 0.84 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL28379714 | 0.84 | PDE3A (0.47) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL3038818 | 0.83 | PDE3A (0.52) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL992472 | 0.83 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL51650 | 0.83 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL4971926 | 0.83 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL27544566 | 0.83 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL7794942 | 0.83 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL2118776 | 0.82 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3503866-B1 | COMPOSITIONS COMPRISING ISOHEXIDE DIESTERS OF C18 FATTY ACIDS AND THEIR USE IN METHODS FOR RESTORING EPIDERMAL INTEGRITY AND FUNCTION AND TREATING DERMATOLOGICAL DISEASES | SYTHEON LTD (US) | 2025-12-03 | — | — | EP | disclosed |
| US-20240398760-A1 | CHELATED, STABLE OPHTHALMOLOGICAL COMPOSITIONS OF KETOROLAC AND PHENYLEPHRINE AND APPLICATIONS THEREOF | SOMERSET THERAPEUTICS, LLC | 2024-12-05 | — | — | US | disclosed |
| US-12102632-B2 | Quinolone dispersions | SOMERSET THERAPEUTICS, LLC (US) | 2024-10-01 | — | — | US | disclosed |
| US-12029729-B2 | Chelated, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof | SOMERSET THERAPEUTICS, LLC (US) | 2024-07-09 | — | — | US | disclosed |
| US-12016855-B2 | Prednisolone and moxifloxacin compositions and methods | SOMERSET THERAPEUTICS, LLC (US) | 2024-06-25 | — | — | US | disclosed |
| US-12012416-B2 | Compositions and methods for treating atopic dermatitis | SYTHEON LTD (US) | 2024-06-18 | — | — | US | disclosed |
| US-11883382-B2 | Buffer-free ophthalmological compositions of ketorolac and phenylephrine and applications thereof | SOMERSET THERAPEUTICS, LLC (US) | 2024-01-30 | — | — | US | disclosed |
| US-11850249-B2 | Methods of efficiently reducing intraocular pressure | SOMERSET THERAPEUTICS, LLC (US) | 2023-12-26 | — | — | US | disclosed |
| US-11793789-B2 | Treatment of ophthalmological conditions using buffer-free ophthalmological compositions of ketorolac and phenylephrine | SOMERSET THERAPEUTICS, LLC (US) | 2023-10-24 | — | — | US | disclosed |
| US-11753414-B2 | Compositions and methods for treating atopic dermatitis | SYTHEON LTD (US) | 2023-09-12 | — | — | US | disclosed |
| US-4609548-A | NON-PRODUCERS OF THYMIDINE KINASE; VETERINARY MEDICINE | NOVAGENE, LTD. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4603112-A | Modified vaccinia virus | HEALTH RESEARCH, INCORPORATED (US) | 1986-07-29 | — | — | US | disclosed |
| US-4579821-A | FUSION OF DNA PROMOTHER/REGULATOR WITH GENES | UNIVERSITY PATENTS, INC. (US) | 1986-04-01 | — | — | US | disclosed |
| EP-0094428-A4 | CONTROL OF DNA SEQUENCE TRANSCRIPTION. | UNIVERSITY PATENTS INC (US) | 1986-01-07 | — | — | EP | disclosed |
| EP-0149040-A2 | Modified live pseudorabies viruses, vaccines for pseudorabies disease containing same, methods for production of same and methods for use of same | NOVAGENE, INC. (US) | 1985-07-24 | — | — | EP | disclosed |
| US-4514497-A | DO NOT PRODUCE THYMIDINE KINASE- TEMPERATURE RESISTANCE | NOVAGENE, LTD. (US) | 1985-04-30 | — | — | US | disclosed |
| US-4465769-A | Non-transformed thymidine kinaseless cell line and its use for testing tumorigenic potential of genes | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0094428-A1 | CONTROL OF DNA SEQUENCE TRANSCRIPTION. | UNIVERSITY PATENTS INC (US) | 1983-11-23 | — | — | EP | disclosed |
| EP-0083286-A2 | Modified vaccinia virus and methods for making and using the same | HEALTH RESEARCH, INCORPORATED (US) | 1983-07-06 | — | — | EP | disclosed |
| WO-1983001783-A1 | CONTROL OF DNA SEQUENCE TRANSCRIPTION | UNIVERSITY PATENTS INC (US) | 1983-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12102632-B2 | Quinolone dispersions | F12, CFD, NFKBIA | PDE3A 374/4885PDE4D 727/4885SLC29A1 1709/4885 |
| US-12029729-B2 | Chelated, stable ophthalmological compositions of ketorolac and phenylephrine and applications thereof | CRYZ, UACA, MYOC | PDE3A 27/4885PDE4D 425/4885SLC29A1 1675/4885 |
| US-11793789-B2 | Treatment of ophthalmological conditions using buffer-free ophthalmological compositions of ketorolac and phenylephrine | CRYZ, MYOC, KIF23 | PDE3A 19/4885PDE4D 314/4885SLC29A1 2530/4885 |
| US-20240398760-A1 | CHELATED, STABLE OPHTHALMOLOGICAL COMPOSITIONS OF KETOROLAC AND PHENYLEPHRINE AND APPLICATIONS THEREOF | CRYZ, UACA, MYOC | PDE3A 27/4885PDE4D 425/4885SLC29A1 1675/4885 |
| US-12012416-B2 | Compositions and methods for treating atopic dermatitis | EBP, TSLP, COL14A1 | PDE3A 1142/4885PDE4D 1176/4885SLC29A1 3525/4885 |
| US-11850249-B2 | Methods of efficiently reducing intraocular pressure | ADRB2, CA2, ADRA2A | PDE3A 19/4885PDE4D 57/4885SLC29A1 1408/4885 |
| US-11883382-B2 | Buffer-free ophthalmological compositions of ketorolac and phenylephrine and applications thereof | CRYZ, MYOC, PDE6C | PDE3A 6/4885PDE4D 136/4885SLC29A1 2181/4885 |
| US-12016855-B2 | Prednisolone and moxifloxacin compositions and methods | SERPINA6, PF4, F12 | PDE3A 580/4885PDE4D 728/4885SLC29A1 2774/4885 |
| US-11753414-B2 | Compositions and methods for treating atopic dermatitis | DHCR7, CYP46A1, NR1H3 | PDE3A 1462/4885PDE4D 1249/4885SLC29A1 3538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.