SCHEMBL3424972

SCHEMBL3424972

O=C(O)CCc1ccccc1Oc1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.64
HRH1 P35367 1/20 0.50
CAMK2A Q9UQM7 1/20 0.50
PCNA P12004 1/20 0.50
FFAR4 Q5NUL3 7/20 0.49
POLB P06746 1/20 0.48
LTA4H P09960 1/20 0.47
NR1H2 P55055 1/20 0.47
BAX Q07812 1/20 0.47
SRD5A2 P31213 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2349794 0.91 FFAR1 (0.58) FFAR1HRH1CAMK2APCNAFFAR4
SCHEMBL3503975 0.90 FFAR1 (0.67) FFAR1HRH1CAMK2AFFAR4SRD5A2
SCHEMBL2353783 0.84 CAMK2A (0.69) FFAR1HRH1CAMK2AFFAR4LTA4H
SCHEMBL25936968 0.84 FFAR1 (0.56) FFAR1HRH1FFAR4
SCHEMBL3424980 0.83 CAMK2A (0.73) FFAR1CAMK2APCNAFFAR4POLB
SCHEMBL8495825 0.80 HRH1 (0.61) FFAR1HRH1CAMK2AFFAR4POLB
SCHEMBL3809518 0.79 FFAR1 (0.58) FFAR1HRH1CAMK2AFFAR4SRD5A2
SCHEMBL6936340 0.79 HRH1 (0.50) FFAR1HRH1LTA4HNR1H2BAX
SCHEMBL1745598 0.79 FFAR1 (1.00) FFAR1FFAR4
SCHEMBL1666512 0.79 SLC1A5 (0.57) FFAR1HRH1PCNALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8476399-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-07-02 US disclosed
US-20130085238-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-04-04 US disclosed
US-8252887-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-08-28 US disclosed
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY (US) 2010-09-16 US disclosed
WO-2010042918-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2010-04-15 WO disclosed
CN-100422129-C Production process of optically pure 2- (4-hydroxyphenoxy) - propionic acid compounds SYNGENTA LTD (GB) 2008-10-01 CN disclosed
CN-1852884-A Preparation method of optically pure 2- (4-hydroxyphenoxy) -propionic acid compound SYNGENTA LTD (GB) 2006-10-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES ECPAS, PTGIR, RXFP1 FFAR1 827/4885HRH1 920/4885CAMK2A 3861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.