SCHEMBL3424980

SCHEMBL3424980

O=C(O)CCc1ccc(O)cc1Oc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 3/20 0.73
FFAR1 O14842 6/20 0.52
POLB P06746 1/20 0.50
FFAR4 Q5NUL3 4/20 0.48
PTGER1 P34995 1/20 0.46
PTGER4 P35408 1/20 0.46
PTGER3 P43115 1/20 0.46
PTGER2 P43116 1/20 0.46
PCNA P12004 1/20 0.46
SRD5A2 P31213 1/20 0.46
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2349799 0.93 CAMK2A (0.71) CAMK2AFFAR1FFAR4PTGER1PTGER4
SCHEMBL2353793 0.84 CAMK2A (1.00) CAMK2A
SCHEMBL15434176 0.84 PTGER4 (0.52) CAMK2AFFAR1FFAR4PTGER1PTGER4
SCHEMBL3424972 0.83 FFAR1 (0.64) CAMK2AFFAR1POLBFFAR4PCNA
SCHEMBL3503975 0.82 FFAR1 (0.67) CAMK2AFFAR1FFAR4PTGER1PTGER4
SCHEMBL4841064 0.80 POLB (0.62) CAMK2AFFAR1POLB
SCHEMBL1666514 0.79 CAMK2A (0.60) CAMK2APCNA
SCHEMBL2349794 0.78 FFAR1 (0.58) CAMK2AFFAR1FFAR4PTGER1PTGER4
SCHEMBL5015511 0.77 POLB (0.51) CAMK2APOLB
SCHEMBL1271016 0.77 CAMK2A (0.57) CAMK2AFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252887-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-08-28 US disclosed
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY (US) 2010-09-16 US disclosed
WO-2010042918-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2010-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES ECPAS, PTGIR, RXFP1 CAMK2A 3861/4885FFAR1 827/4885POLB 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.