SCHEMBL1666514

SCHEMBL1666514

NC(CCc1ccc(O)cc1Oc1ccccc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 3/20 0.60
LTA4H P09960 1/20 0.45
SLC1A5 Q15758 6/20 0.45
KIF11 P52732 1/20 0.43
PCNA P12004 1/20 0.41
P2RY10 O00398 1/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
CYP3A4 P08684 1/20 0.40
HTR1A P08908 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
NFKB1 P19838 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
SLC6A4 P31645 1/20 0.40
HTR7 P34969 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666604 0.86 CAMK2A (0.63) CAMK2ALTA4HPCNAKDM4EALDH1A1
SCHEMBL1666512 0.85 SLC1A5 (0.57) LTA4HSLC1A5KIF11PCNAP2RY10
SCHEMBL3424980 0.79 CAMK2A (0.73) CAMK2APCNA
SCHEMBL2349799 0.78 CAMK2A (0.71) CAMK2A
SCHEMBL2353793 0.76 CAMK2A (1.00) CAMK2ALTA4HHSD17B10PLA2G10
SCHEMBL28075883 0.75 CYP3A4 (0.47) KIF11KDM4EALDH1A1LMNACYP3A4
SCHEMBL1666509 0.72 SLC1A5 (0.51) LTA4HSLC1A5KDM4EADORA3ALOX15
SCHEMBL16147892 0.72 SLC1A5 (0.53) SLC1A5KIF11KMT2A
SCHEMBL16147891 0.72 SLC1A5 (0.53) SLC1A5KIF11KMT2A
SCHEMBL28741601 0.72 SLC1A5 (0.53) SLC1A5KIF11KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118011-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-09-14 US disclosed
EP-3461855-B1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES UNIV RUTGERS (US) 2020-05-27 EP disclosed
US-20190185624-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2019-06-20 US disclosed
EP-3461855-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2019-04-03 EP disclosed
US-10202490-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-02-12 US disclosed
EP-2486081-B1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES UNIV RUTGERS (US) 2018-12-05 EP disclosed
US-20170158819-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2017-06-08 US disclosed
US-9605112-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-03-28 US disclosed
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-09-06 US disclosed
EP-2486081-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES Rutgers, The State University of New Jersey (US) 2012-08-15 EP disclosed
WO-2011044567-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES MATR3, MIF, BMP2 CAMK2A 4182/4885LTA4H 1151/4885SLC1A5 3187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.