SCHEMBL3425324

SCHEMBL3425324

O=P(O)(O)CN(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 3/20 0.46
ANPEP P15144 3/20 0.46
HPGD P15428 1/20 0.45
ACP3 P15309 2/20 0.44
TSHR P16473 3/20 0.44
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
CFTR P13569 1/20 0.43
ERAP1 Q9NZ08 2/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA5A P35218 1/20 0.43
ERAP2 Q6P179 1/20 0.43
FDPS P14324 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1655196 0.96 LAP3 (0.46) LAP3ANPEPHPGDACP3TSHR
SCHEMBL10383331 0.94 LAP3 (0.44) LAP3ANPEPHPGDACP3TSHR
SCHEMBL7192594 0.87 HTT (0.50) LAP3ANPEPHPGDTSHRALDH1A1
SCHEMBL6833041 0.87 LAP3 (0.40) LAP3ANPEPHPGDNPC1RAB9A
SCHEMBL9505404 0.84 ALOX15 (0.41) LAP3ANPEPHPGDACP3TSHR
SCHEMBL9715390 0.82 LAP3 (0.44) LAP3ANPEPHPGDACP3TSHR
SCHEMBL24673276 0.81 CNR2 (0.43) HPGDTSHRALDH1A1MEN1KMT2A
SCHEMBL9505356 0.81 ANPEP (0.40) LAP3ANPEPACP3ALDH1A1ERAP1
SCHEMBL12227404 0.80 MEN1 (0.50) LAP3ANPEPHPGDTSHRALDH1A1
SCHEMBL9315590 0.79 TSHR (0.53) LAP3ANPEPHPGDTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7750180-B2 Process for the preparation of N-phosphonomethylglycine and derivatives thereof MONSANTO TECHNOLOGY LLC (US) 2010-07-06 US disclosed
EP-1664068-A2 PROCESS FOR THE PREPARATION OF N-PHOSPHONO-METHYLGLYCINE AND DERIVATIVES THEREOF Monsanto Technology, LLC (US) 2006-06-07 EP disclosed
US-20050054871-A1 Process for the preparation of N-phosphonomethylglycine and derivatives thereof MONSANTO TECHNOLOGY LLC 2005-03-10 US disclosed
WO-2005019230-A2 PROCESS FOR THE PREPARATION OF N-PHOSPHONO-METHYLGLYCINE AND DERIVATIVES THEREOF MONSANTO TECHNOLOGY LLC (US) 2005-03-03 WO disclosed
EP-0078766-B1 PROCESS FOR PREPARING AMINOMETHYLPHOSPHONIC ACID CIBA-GEIGY AG (CH) 1985-04-17 EP disclosed
EP-0078766-A1 Process for preparing aminomethylphosphonic acid CIBA-GEIGY AG (CH) 1983-05-11 EP disclosed
US-4368162-A Process for producing aminomethylphosphonic acid CIBA-GEIGY CORPORATION (US) 1983-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054871-A1 Process for the preparation of N-phosphonomethylglycine and derivatives thereof PHOSPHO1, GNE, MPHOSPH6 LAP3 667/4885ANPEP 85/4885HPGD 648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.