Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 16/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3428079 | 0.88 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3419619 | 0.87 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL633151 | 0.87 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL633150 | 0.87 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3396541 | 0.87 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL3629365 | 0.85 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL3669711 | 0.81 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL3631921 | 0.80 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3627358 | 0.79 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL3666412 | 0.78 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245028-A1 | 5-AMINOCYCLYLMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-11-03 | — | — | EP | claimed |
| WO-2009077989-A1 | 5-AMINOCYCLYLMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-06-25 | — | — | WO | claimed |
| EP-2245028-A1 | 5-AMINOCYCLYLMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009077989-A1 | 5-AMINOCYCLYLMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-06-25 | — | — | WO | disclosed |