Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425873 | 0.79 | CES1 (0.34) | CCR1CCR5CCR8HDAC8HPGD | |
| SCHEMBL12578985 | 0.75 | NOS3 (0.52) | LMNAKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL5740853 | 0.75 | ALDH1A1 (0.41) | CCR1CCR5CCR8HDAC8GRM5 | |
| SCHEMBL2562927 | 0.74 | NOTUM (0.46) | HPGDRAB9ANPC1SMN1; SMN2THRB | |
| SCHEMBL31175957 | 0.73 | CLK4 (0.42) | LMNAKDM4EMAPTHTTRAB9A | |
| SCHEMBL14886517 | 0.70 | CYP3A4 (0.43) | CCR1CCR5CCR8HDAC8MAPT | |
| SCHEMBL27879319 | 0.70 | CYP3A4 (0.47) | CCR1CCR5CCR8GRM5NR4A2 | |
| SCHEMBL16574215 | 0.70 | IDO1 (0.46) | KDM4ERAB9ANPC1SMN1; SMN2THRB | |
| SCHEMBL13910997 | 0.69 | CLK4 (0.42) | CCR1CCR5CCR8HDAC8LMNA | |
| SCHEMBL7450182 | 0.69 | CCR1 (0.55) | CCR1CCR5CCR8HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731985-B2 | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| EP-1484971-B1 | USE OF 4-AMINOPYRIMIDINES FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SC HOLDING AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| CN-1642422-A | 4-aminopyrimidines and their use in the antimicrobial treatment of surfaces | CIBA SC HOLDING AG (CH) | 2005-07-20 | — | — | CN | disclosed |
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | CIBA SPECIALTY CHEMICALS CORP. | 2005-06-30 | — | — | US | disclosed |
| EP-1484971-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | Ciba SC Holding AG (CH) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003077656-A1 | 4-AMINOPYRIMIDINES AND THEIR USE FOR THE ANTIMICROBIAL TREATMENT OF SURFACES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143387-A1 | 4-Aminopyrimidines and their use for the antimicrobial treatment of surfaces | DPM1, UNG, DPYD | CCR1 2215/4885CCR5 2522/4885CCR8 2712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.