Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | EGFR | P00533 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426371 | 1.00 | ALDH1A1 (0.62) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL3426556 | 0.99 | ALDH1A1 (0.61) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL3426559 | 0.99 | ALDH1A1 (0.61) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| SCHEMBL13400602 | 0.88 | ALDH1A1 (0.56) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| SCHEMBL3427068 | 0.88 | ALDH1A1 (0.56) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| SCHEMBL3427066 | 0.88 | ALDH1A1 (0.56) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| SCHEMBL13400607 | 0.84 | ALDH1A1 (0.52) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL3427923 | 0.84 | ALDH1A1 (0.51) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL3427928 | 0.84 | ALDH1A1 (0.51) | ALDH1A1EGFRKDM4EL3MBTL1HPGD | |
| SCHEMBL13400603 | 0.80 | HTR7 (0.39) | ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700306-B2 | characterising a polypeptide by matrix assisted laser desorption ionization (MALDI) mass spectrometry; improving sensitivity, and can increase the number of peptides that are detected from a protein | ELECTROPHORETICS LIMITED (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20060040334-A1 | Method for characterising analytes | XZILLION GMBH & CO. KG (DE) | 2006-02-23 | — | — | US | disclosed |