Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 8/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.76 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.76 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.76 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.60 |
| ▸ | BCL2L2 | Q92843 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | BAD | Q92934 | 3/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426375 | 1.00 | BCL2 (0.76) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL3426376 | 1.00 | BCL2 (0.76) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL19425453 | 1.00 | BCL2 (0.76) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL4264548 | 0.87 | BCL2 (1.00) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL158040 | 0.87 | BCL2 (1.00) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL158041 | 0.87 | BCL2 (1.00) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL19420059 | 0.85 | BCL2 (0.54) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL13982547 | 0.83 | BCL2 (0.80) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL13812532 | 0.83 | BCL2 (0.80) | BCL2MEN1KMT2AMCL1BCL2L1 | |
| SCHEMBL5970105 | 0.83 | BCL2 (0.80) | BCL2MEN1KMT2AMCL1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024783-A1 | BIARYLRHODANINE AND PYRIDYLRHODANINE COMPOUNDS AND THEIR USE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-03-04 | — | — | WO | disclosed |