Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.54 |
| ▸ | BCL2L2 | Q92843 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19425453 | 0.85 | BCL2 (0.76) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL3426372 | 0.85 | BCL2 (0.76) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL3426375 | 0.85 | BCL2 (0.76) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL3426376 | 0.85 | BCL2 (0.76) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL19420037 | 0.76 | MCL1 (0.52) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL19420029 | 0.75 | MCL1 (0.71) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL19420033 | 0.75 | MCL1 (0.49) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL19420041 | 0.74 | MCL1 (0.53) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL19420056 | 0.72 | MCL1 (0.48) | BCL2MCL1MEN1KMT2ABCL2L1 | |
| SCHEMBL13461486 | 0.72 | BCL2 (0.67) | BCL2MCL1MEN1KMT2ABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | TP53, NQO1, SHMT2 | BCL2 520/4885MCL1 137/4885MEN1 3416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.