Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872227 | 0.76 | — | — | |
| SCHEMBL5917 | 0.73 | CYP2A6 (0.35) | KCNJ1 | |
| SCHEMBL9872905 | 0.72 | — | — | |
| SCHEMBL9872511 | 0.72 | SNCA (0.30) | — | |
| SCHEMBL5318854 | 0.71 | TRIM24 (0.41) | — | |
| SCHEMBL196009 | 0.69 | — | — | |
| SCHEMBL3397443 | 0.66 | ALDH1A1 (0.37) | KCNJ1 | |
| SCHEMBL31006315 | 0.66 | ALDH1A1 (0.37) | KCNJ1 | |
| SCHEMBL1545888 | 0.66 | — | — | |
| SCHEMBL7211249 | 0.65 | NOTUM (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246348-A1 | Coupling reactions useful in the preparation of (1h-tetrazol-5-yl)-biphenyl derivatives | Novartis AG (CH) | 2010-11-03 | — | — | EP | disclosed |