Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.51 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835323 | 0.95 | PLK1 (0.59) | PLK1FFAR1HTR2AS1PR1S1PR3 | |
| SCHEMBL854760 | 0.95 | PLK1 (0.59) | PLK1FFAR1HTR2AS1PR1S1PR3 | |
| SCHEMBL13093956 | 0.93 | FFAR1 (0.57) | PLK1FFAR1CYP3A4MEN1CYP1A2 | |
| SCHEMBL10931913 | 0.91 | SPHK1 (0.58) | PLK1CYP3A4HTR2AS1PR1S1PR3 | |
| SCHEMBL854394 | 0.88 | HTT (0.59) | PLK1FFAR1CYP3A4MEN1CYP1A2 | |
| SCHEMBL854851 | 0.87 | FFAR1 (0.61) | PLK1FFAR1 | |
| SCHEMBL16093379 | 0.85 | FFAR1 (0.61) | FFAR1CYP3A4MEN1CYP1A2CYP2C9 | |
| SCHEMBL29380232 | 0.83 | ADRA2A (0.52) | PLK1MEN1KMT2AADRA2AKCNH2 | |
| SCHEMBL1845938 | 0.83 | AGER (0.56) | PLK1CYP3A4MEN1CYP1A2CYP2C19 | |
| SCHEMBL855506 | 0.83 | SPHK1 (0.58) | PLK1CYP3A4S1PR1S1PR3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248423-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |