Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 1/20 | 0.54 |
| ▸ | PNP | P00491 | 8/20 | 0.52 |
| ▸ | DHFR | P00374 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21396480 | 0.92 | PNP (0.55) | TK1PNPDHFR | |
| SCHEMBL23921149 | 0.81 | PNP (0.51) | TK1PNPDHFRKDM4EHSD17B10 | |
| SCHEMBL10871605 | 0.80 | PNP (0.59) | TK1PNPHSD17B10 | |
| SCHEMBL23921065 | 0.80 | PNP (0.50) | TK1PNPDHFRKDM4EALDH1A1 | |
| SCHEMBL23921002 | 0.80 | PNP (0.50) | TK1PNPDHFRMAPTKDM4E | |
| SCHEMBL10872975 | 0.80 | PNP (0.73) | TK1PNPHSD17B10 | |
| SCHEMBL10873200 | 0.79 | TK1 (0.59) | TK1PNPHSD17B10 | |
| SCHEMBL20762970 | 0.77 | DHFR (0.67) | PNPDHFRKDM4E | |
| SCHEMBL23921106 | 0.77 | DHFR (0.62) | TK1PNPDHFRKDM4EHSD17B10 | |
| SCHEMBL21396441 | 0.74 | ADORA2A (0.60) | TK1PNPDHFRPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727995-B2 | Antiherpes drug combinations | UNIVERSITY OF MASSACHUSETTS (US) | 2010-06-01 | — | — | US | disclosed |
| EP-1594507-A4 | NOVEL ANTIHERPES DRUG COMBINATIONS | UNIV MASSACHUSETTS (US) | 2008-10-01 | — | — | EP | disclosed |
| EP-1594507-A2 | NOVEL ANTIHERPES DRUG COMBINATIONS | The University of Massachussetts (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20040259832-A1 | Novel antiherpes drug combinations | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-12-23 | — | — | US | disclosed |
| WO-2004069168-A2 | NOVEL ANTIHERPES DRUG COMBINATIONS | UNIVERSITY OF MASSACHUSETTS (US) | 2004-08-19 | — | — | WO | disclosed |
| EP-0794781-A4 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIV MASSACHUSETTS MEDICAL (US) | 1998-04-22 | — | — | EP | disclosed |
| EP-0794781-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996020711-A1 | DRUGS TO PREVENT RECURRENT HERPES VIRUS INFECTIONS | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER (US) | 1996-07-11 | — | — | WO | disclosed |