Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676884 | 0.85 | HPRT1 (0.50) | ERN1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL5749446 | 0.82 | ALDH1A1 (0.37) | ERN1ALDH1A1HSD17B10CYP2A6CYP1A2 | |
| SCHEMBL8723699 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL2155019 | 0.79 | CYP2A6 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL22499801 | 0.76 | CYP2A6 (0.36) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL22499803 | 0.76 | CYP2A6 (0.36) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL16288312 | 0.75 | ALDH1A1 (0.34) | ERN1ALDH1A1HSD17B10TDP1CYP2A6 | |
| SCHEMBL27529422 | 0.73 | CYP2A6 (0.40) | ALDH1A1HSD17B10TDP1CYP2A6CYP1A2 | |
| SCHEMBL28302283 | 0.73 | ESR1 (0.33) | ERN1ALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL20507044 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HSD17B10TDP1CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277934-A | Euphorbia lathyris diterpene derivatives with MDR reversion activity and application thereof | 中国科学院成都生物研究所 | 2021-08-20 | — | — | CN | claimed |
| CN-101646704-A | Method for the production of polyurethane compositions with a low isocyanate monomer content | SIKA TECHNOLOGY AG CH | 2010-02-10 | — | — | CN | claimed |
| US-4505716-A | WETTING AGENTS, DISPERSANTS, CLAY STABILIZER, AGITATION, GELATION | ITT CORPORATION (US) | 1985-03-19 | — | — | US | claimed |
| US-4432771-A | SLURRY WITH DISPERSANT AND CLAY STABILIZERS | INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) | 1984-02-21 | — | — | US | claimed |
| WO-2024113146-A1 | MOISTURE AND HEAT-CURABLE SEALING COMPOSITION | SIKA TECHNOLOGY AG (CH) | 2024-06-06 | — | — | WO | disclosed |
| CN-117358275-A | Carbon nitride molecular junction catalyst and preparation method and application thereof | 深圳大学 | 2024-01-09 | — | — | CN | disclosed |
| CN-113277934-B | Euphorbia lathyris diterpene derivatives with MDR reversion activity and application thereof | 中国科学院成都生物研究所 | 2022-07-15 | — | — | CN | disclosed |
| CN-110003413-A | The preparation method and dihydroxy naphthlene condensation product of dihydroxy naphthlene condensation product | 信越化学工业株式会社 | 2019-07-12 | — | — | CN | disclosed |
| CN-109960111-A | Organic film forms the forming method and pattern forming method with composition, semiconductor device producing substrate, organic film | 信越化学工业株式会社 | 2019-07-02 | — | — | CN | disclosed |
| US-10189947-B2 | Composition of anti-reflective hardmask | CHOI SANG JUN (KR) | 2019-01-29 | — | — | US | disclosed |
| CN-107286144-A | A kind of new imidazolium compounds and its use for electronic equipment material, light-emitting component and electronic installation | 昱镭光电科技股份有限公司 | 2017-10-24 | — | — | CN | disclosed |
| US-20170198096-A1 | Composition of Anti-Reflective Hardmask | CHOI SANG JUN (KR) | 2017-07-13 | — | — | US | disclosed |
| EP-0534257-A1 | Salicylic acid derivatives, the process for preparing the same and the heat-sensitive recording materials comprising thereof | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4505716-A | WETTING AGENTS, DISPERSANTS, CLAY STABILIZER, AGITATION, GELATION | ITT CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |
| US-4374261-A | CENTRAL NERVOUS SYSTEM STIMULANTS | HOFFMANN-LA ROCHE INC. (US) | 1983-02-15 | — | — | US | disclosed |
| US-4314063-A | INTERMEDIATES FOR CNS STIMULANTS | HOFFMANN-LA ROCHE INC. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4278798-A | STIMULANTS | HOFFMANN-LA ROCHE INC. (US) | 1981-07-14 | — | — | US | disclosed |
| US-4260816-A | HYPOGLYCEMIC, HYPOLIPIDEMIC AGENTS, TREATMENT OF DIABETES | AMERICAN CYANAMID COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4104468-A | 1,3,4-Oxadiazolyl-(2)-vinyl stilbene optical brighteners | SANDOZ LTD. (CH) | 1978-08-01 | — | — | US | disclosed |
| US-3953524-A | Catalytic hydrogenation of alpha,beta-unsaturated aldehydes to alpha,beta-unsaturated alcohols | HOFFMANN-LA ROCHE INC. (US) | 1976-04-27 | — | — | US | disclosed |