SCHEMBL2155019

SCHEMBL2155019

[CH]=Cc1[c]ccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.39
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 3/20 0.39
TSHR P16473 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
HPRT1 P00492 1/20 0.36
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
CYP1A2 P05177 3/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
KEAP1 Q14145 1/20 0.32
PTPN22 Q9Y2R2 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057576 0.85 HPRT1 (0.50) CYP2A6ALDH1A1HSD17B10TSHRTDP1
SCHEMBL1619946 0.82 ALDH1A1 (0.34) ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL5050174 0.81 ALDH1A1 (0.33) ALDH1A1HSD17B10TDP1HIF1ACYP1B1
SCHEMBL342713 0.79 ERN1 (0.41) CYP2A6ALDH1A1HSD17B10TSHRTDP1
SCHEMBL8723699 0.79 ALDH1A1 (0.39) CYP2A6ALDH1A1HSD17B10TSHRTDP1
SCHEMBL22499801 0.76 CYP2A6 (0.36) CYP2A6ALDH1A1HSD17B10TSHRTDP1
SCHEMBL22499803 0.76 CYP2A6 (0.36) CYP2A6ALDH1A1HSD17B10TSHRTDP1
SCHEMBL5052600 0.75 ALDH1A1 (0.33) ALDH1A1HSD17B10CYP1A2HPGD
SCHEMBL16288312 0.75 ALDH1A1 (0.34) CYP2A6ALDH1A1HSD17B10TSHRTDP1
SCHEMBL5052509 0.73 ALDH1A1 (0.45) ALDH1A1HSD17B10TDP1CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2196847-B1 ELECTROCHROMIC DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME KURARAY CO (JP) 2013-12-11 EP claimed
US-8233211-B2 Electrochromic display device and its manufacturing method KURARAY CO., LTD. (JP) 2012-07-31 US claimed
EP-1744722-B1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC BLOCK COPOLYMER OREAL (FR) 2011-07-13 EP claimed
US-20100328751-A1 ELECTROCHROMIC DISPLAY DEVICE AND ITS MANUFACTURING METHOD KURARAY CO., LTD. (JP) 2010-12-30 US claimed
EP-2196847-A1 ELECTROCHROMIC DISPLAY DEVICE AND METHOD FOR MANUFACTURING THE SAME Kuraray Co., Ltd. (JP) 2010-06-16 EP claimed
EP-1748754-B1 COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC BLOCK COPOLYMER OREAL (FR) 2009-07-22 EP claimed
US-20080138635-A1 Conjugated Organic Molecules for Molecular Electronic Devices NATIONAL UNIVERSITY OF SINGAPORE (SG) 2008-06-12 US claimed
US-20070224151-A1 Cosmetic Composition Comprising at Least One Specific Block Copolymer L'OREAL (FR) 2007-09-27 US claimed
EP-0946993-B8 ELECTRODE DEPOSITION FOR ORGANIC LIGHT-EMITTING DEVICES CAMBRIDGE DISPLAY TECH LTD (GB) 2007-09-12 EP claimed
US-20070172505-A1 Cosmetic composition comprising at least one specific block copolymer LOREAL (FR) 2007-07-26 US claimed
US-20030092878-A1 Composite type conductive polymer and process of producing aromatic compound TOYODA GOSEI CO., LTD. (JP) 2003-05-15 US claimed
US-20030044645-A1 Organic EL device and preparation method TDK CORPORATION (JP) 2003-03-06 US claimed
EP-1285957-A2 Organic electroluminescent device and method of its preparation TDK Corporation (JP) 2003-02-26 EP claimed
US-20030013912-A1 Self-doped conductive polymer, monomer for synthesizing self-doped conductive polymer, and processes of producing the same TOYODA GOSEI CO., LTD. (JP) 2003-01-16 US claimed
EP-1273569-A1 Self-doped conductive polymer, monomer for synthesizing self-doped conductive polymer, and processes of producing the same Toyoda Gosei Co., Ltd. (JP) 2003-01-08 EP claimed
EP-1267359-A2 Composite type electroconductive polymer and process of producing an aromatic compound Toyoda Gosei Co., Ltd. (JP) 2002-12-18 EP claimed
US-6488555-B2 Electrode deposition for organic light-emitting devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2002-12-03 US claimed
US-20020109458-A1 Electrode deposition for organic light-emitting devices CAMBRIDGE DISPLAY TECHNOLOGY LIMITED 2002-08-15 US claimed
EP-0946993-A1 ELECTRODE DEPOSITION FOR ORGANIC LIGHT-EMITTING DEVICES Cambridge Display Technology Limited (GB) 1999-10-06 EP claimed
WO-1998010473-A1 ELECTRODE DEPOSITION FOR ORGANIC LIGHT-EMITTING DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 1998-03-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070172505-A1 Cosmetic composition comprising at least one specific block copolymer COIL, CRYAB, TBCB CYP2A6 2104/4885ALDH1A1 335/4885HSD17B10 150/4885
US-20030092878-A1 Composite type conductive polymer and process of producing aromatic compound KCNH1, PIEZO1, KCNH3 CYP2A6 2875/4885ALDH1A1 2832/4885HSD17B10 1772/4885
US-20070224151-A1 Cosmetic Composition Comprising at Least One Specific Block Copolymer FABP4, HSD17B4, LRBA CYP2A6 1515/4885ALDH1A1 370/4885HSD17B10 21/4885
US-20030013912-A1 Self-doped conductive polymer, monomer for synthesizing self-doped conductive polymer, and processes of producing the same HCN2, HCN4, HCN1 CYP2A6 311/4885ALDH1A1 1135/4885HSD17B10 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.