Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786507 | 1.00 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL1784565 | 0.78 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL3407447 | 0.78 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL9432019 | 0.77 | SLC6A2 (0.52) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL78044 | 0.76 | DRD4 (0.51) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL8924483 | 0.76 | DRD4 (0.51) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL18689815 | 0.73 | HRH1 (0.43) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL6978725 | 0.73 | GFER (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B | |
| SCHEMBL21254392 | 0.73 | DRD4 (0.52) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27658505 | 0.73 | DRD2 (0.51) | SLC6A2SLC6A4SLC6A3HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252293-A2 | KINASE INHIBITORS AND METHODS OF USE | Intellikine, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009114870-A2 | KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE, INC. (US) | 2009-09-17 | — | — | WO | disclosed |
| WO-2009114874-A2 | BENZOTHIAZOLE KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE, INC. (US) | 2009-09-17 | — | — | WO | disclosed |