Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.42 |
| ▸ | PPARD | Q03181 | 7/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | FABP4 | P15090 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620138 | 0.86 | ZDHHC20 (0.31) | — | |
| SCHEMBL28451419 | 0.81 | ZDHHC20 (0.44) | TSHRGPR84PPARGPPARDPPARA | |
| SCHEMBL10881427 | 0.81 | ZDHHC20 (0.44) | TSHRGPR84PPARGPPARDPPARA | |
| SCHEMBL513833 | 0.75 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL10499255 | 0.74 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL1200063 | 0.74 | TSHR (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| Water SCHEMBL11318112 | 0.71 | KDM4A (0.66) | TSHRLMNANFKB1PMP22GPR84 | |
| Water SCHEMBL11562837 | 0.71 | KDM4A (0.66) | TSHRLMNANFKB1PMP22GPR84 | |
| Water SCHEMBL11662612 | 0.71 | KDM4A (0.66) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL11709128 | 0.71 | TSHR (0.50) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700306-B2 | characterising a polypeptide by matrix assisted laser desorption ionization (MALDI) mass spectrometry; improving sensitivity, and can increase the number of peptides that are detected from a protein | ELECTROPHORETICS LIMITED (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20060040334-A1 | Method for characterising analytes | XZILLION GMBH & CO. KG (DE) | 2006-02-23 | — | — | US | disclosed |