SCHEMBL513833

SCHEMBL513833

CC(=O)N(I)CCCCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
LMNA P02545 2/20 0.50
NFKB1 P19838 1/20 0.50
PMP22 Q01453 1/20 0.50
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 7/20 0.46
PPARD Q03181 7/20 0.46
PPARA Q07869 7/20 0.46
HDAC11 Q96DB2 5/20 0.46
PTPN1 P18031 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46
ALOX15 P16050 1/20 0.46
PDE4A P27815 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31239023 0.78 DNM1 (0.42) TSHRGPR84PPARGPPARDPPARA
SCHEMBL1200063 0.78 TSHR (0.55) TSHRLMNANFKB1PMP22GPR84
SCHEMBL10499255 0.78 TSHR (0.55) TSHRLMNANFKB1PMP22GPR84
SCHEMBL6518459 0.75 TSHR (0.50) TSHRLMNANFKB1PMP22GPR84
SCHEMBL11709128 0.75 TSHR (0.50) TSHRLMNANFKB1PMP22GPR84
SCHEMBL11252438 0.74 EPHX2 (0.50) TSHRLMNANFKB1PMP22GPR84
Octanedioate SCHEMBL1539264 0.74 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL1539243 0.74 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL15111284 0.74 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84
Pimelic Acid SCHEMBL28802731 0.74 TSHR (0.80) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3148577-B1 NOVEL SEMI-SYNTHETIC MENINGOCOCCAL CONJUGATE VACCINE BIOLOGICAL E LTD (IN) 2021-01-20 EP claimed
US-20170198004-A1 NOVEL SEMI-SYNTHETIC MENINGOCOCCAL CONJUGATE VACCINE BIOLOGICAL E LTD (IN) 2017-07-13 US claimed
EP-3148577-A2 NOVEL SEMI-SYNTHETIC MENINGOCOCCAL CONJUGATE VACCINE Biological E Limited (IN) 2017-04-05 EP claimed
WO-2015181834-A2 NOVEL SEMI-SYNTHETIC MENINGOCOCCAL CONJUGATE VACCINE BIOLOGICAL E LIMITED (IN) 2015-12-03 WO claimed
US-20110229510-A1 GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2011-09-22 US claimed
EP-2315771-A2 GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF Sloan Kettering Institute For Cancer Research (US) 2011-05-04 EP claimed
WO-2010006343-A2 GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 2010-01-14 WO claimed
EP-0996455-B1 ALPHA-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF SLOAN KETTERING INST CANCER (US) 2009-12-16 EP claimed
US-20240238328-A1 Sulfated Glycosaminoglycan Biomaterials as Proteoglycan Mimics GLYCOLOGIX INC (US) 2024-07-18 US disclosed
US-11975019-B2 Sulfated glycosaminoglycan biomaterials as proteoglycan mimics GLYCOLOGIX, INC. (US) 2024-05-07 US disclosed
US-11911411-B2 Sulfated glycosaminoglycan biomaterials as proteoglycan mimics GLYCOLOGIX, INC. (US) 2024-02-27 US disclosed
CN-115697352-A Sulfated glycosaminoglycan biomaterials as proteoglycan mimetics 格莱克罗吉克斯公司 2023-02-03 CN disclosed
EP-4121064-A1 SULFATED GLYCOSAMINOGLYCAN BIOMATERIALS AS PROTEOGLYCAN MIMICS Glycologix, Inc. (US) 2023-01-25 EP disclosed
US-11420993-B2 Semi-synthetic meningococcal conjugate vaccine BIOLOGICAL E LIMITED 2022-08-23 US disclosed
US-20030083235-A1 Alpha-o-linked glycoconjugates, methods of preparation and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-05-01 US disclosed
EP-1091751-A1 TRIMERIC ANTIGENIC O-LINKED GLYCOPEPTIDE CONJUGATES, METHODS OF PREPARATION AND USES THEREOF Sloan-Kettering Institute For Cancer Research (US) 2001-04-18 EP disclosed
EP-0996455-A1 $g(a)-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF Sloan-Kettering Institute For Cancer Research (US) 2000-05-03 EP disclosed
WO-1999048515-A9 TRIMERIC ANTIGENIC O-LINKED GLYCOPEPTIDE CONJUGATES, METHODS OF PREPARATION AND USES THEREOF SLOAN KETTERING INST CANCER (US) 1999-11-25 WO disclosed
WO-1999048515-A1 TRIMERIC ANTIGENIC O-LINKED GLYCOPEPTIDE CONJUGATES, METHODS OF PREPARATION AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1999-09-30 WO disclosed
WO-1998046246-A1 α-O-LINKED GLYCOCONJUGATES WITH CLUSTERED (2,6)-ST EPITOPES, METHODS OF PREPARATION AND USES THEREOF SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1998-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238328-A1 Sulfated Glycosaminoglycan Biomaterials as Proteoglycan Mimics MATR3, CSGALNACT1, CD44 TSHR 1596/4885LMNA 1160/4885NFKB1 4229/4885
US-11420993-B2 Semi-synthetic meningococcal conjugate vaccine STT3B, CD14, DDOST TSHR 4048/4885LMNA 3410/4885NFKB1 750/4885
US-20170198004-A1 NOVEL SEMI-SYNTHETIC MENINGOCOCCAL CONJUGATE VACCINE STT3B, CD14, STT3A TSHR 3998/4885LMNA 3181/4885NFKB1 853/4885
US-11911411-B2 Sulfated glycosaminoglycan biomaterials as proteoglycan mimics MATR3, CSGALNACT1, CD44 TSHR 1596/4885LMNA 1160/4885NFKB1 4229/4885
US-20110229510-A1 GLYCOPEPTIDE CONSTRUCTS AND USES THEREOF B3GAT3, MICA, SIGLEC7 TSHR 2791/4885LMNA 4097/4885NFKB1 3297/4885
US-11975019-B2 Sulfated glycosaminoglycan biomaterials as proteoglycan mimics CSGALNACT1, MATR3, CD44 TSHR 1659/4885LMNA 1956/4885NFKB1 4562/4885
US-20030083235-A1 Alpha-o-linked glycoconjugates, methods of preparation and uses thereof MUC1, FUT5, FUT6 TSHR 2210/4885LMNA 3345/4885NFKB1 3872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.