Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7875753 | 0.88 | CA2 (0.59) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL1487288 | 0.82 | CA2 (0.54) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL1700171 | 0.82 | CA2 (0.54) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL12967131 | 0.82 | CA2 (0.54) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL1786903 | 0.82 | CA2 (0.54) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL12921173 | 0.81 | CA2 (0.53) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL9580528 | 0.80 | ALDH1A1 (0.56) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL46416 | 0.80 | ALDH1A1 (0.56) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL9778093 | 0.80 | ALDH1A1 (0.56) | CA2ALDH1A1NPSR1TSHRMAPK1 | |
| SCHEMBL8393672 | 0.80 | CA2 (0.49) | CA2ALDH1A1NPSR1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036928-A1 | PREVENTION AND TREATMENT OF CANCER WITH LKB1 NON-EXPRESSION (DELETION OR MUTATION) | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-04-01 | — | — | WO | disclosed |