Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208171 | 0.81 | PKM (0.58) | PKMGAAFFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL787870 | 0.81 | PKM (0.62) | PKMALDH1A1SMN1; SMN2USP2HPGD | |
| SCHEMBL17285630 | 0.81 | FFAR1 (0.65) | PKMGAAFFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3430422 | 0.79 | PKM (0.56) | PKMGAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL941105 | 0.79 | SMN1; SMN2 (0.66) | PKMGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1251803 | 0.79 | PKM (0.56) | PKMGAAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19389501 | 0.79 | PKM (0.47) | PKMGAAFFAR1ALDH1A1MEN1 | |
| SCHEMBL7407 | 0.78 | FFAR1 (0.68) | PKMGAAFFAR1ALDH1A1MEN1 | |
| SCHEMBL19389461 | 0.78 | PKM (0.54) | PKMGAAFFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14309133 | 0.78 | PKM (0.54) | PKMGAAFFAR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002502-A1 | DIHYDROPYRIMIDINONE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 大日本住友製薬株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |
| WO-2008027466-A1 | HYDANTOIN DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | SCHERING CORPORATION (US) | 2008-03-06 | — | — | WO | disclosed |