SCHEMBL7407

SCHEMBL7407

CC(=O)CSc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.68
PKM P14618 2/20 0.55
MTNR1A P48039 4/20 0.53
MTNR1B P49286 4/20 0.53
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 4/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 2/20 0.49
HSD17B10 Q99714 2/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.48
FKBP1A P62942 2/20 0.47
HSD11B1 P28845 1/20 0.47
POLB P06746 1/20 0.47
LMNA P02545 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL941141 0.88 FFAR1 (0.53) FFAR1PKMMTNR1AMTNR1BMEN1
SCHEMBL2210143 0.85 FFAR1 (0.61) FFAR1MTNR1AMTNR1BMEN1KMT2A
SCHEMBL17285630 0.84 FFAR1 (0.65) FFAR1PKMALDH1A1GAAHSD17B10
SCHEMBL8635949 0.83 FFAR1 (0.63) FFAR1MTNR1AMTNR1BMEN1KMT2A
SCHEMBL74365 0.81 FFAR1 (1.00) FFAR1MEN1KMT2ANPC1ALDH1A1
SCHEMBL94582 0.81 FFAR1 (0.60) FFAR1MTNR1AMTNR1BMEN1KMT2A
SCHEMBL9179407 0.81 FFAR1 (0.74) FFAR1MEN1KMT2ANPC1ALDH1A1
SCHEMBL14309133 0.81 PKM (0.54) FFAR1PKMKMT2AALDH1A1GAA
SCHEMBL6808107 0.80 SMN1; SMN2 (0.53) FFAR1PKMMEN1KMT2ANPC1
SCHEMBL6208171 0.80 PKM (0.58) FFAR1PKMMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110130482-A1 Process for preparing armatic thiophenyl ketones PRETOR ROGER 2011-06-02 US claimed
EP-1799638-B1 PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES CIBA HOLDING INC (CH) 2008-07-30 EP claimed
EP-1799638-A1 PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-06-27 EP claimed
WO-2006034966-A1 PROCESS FOR PREPARING AROMATIC THIOPHENYL KETONES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-04-06 WO claimed
US-4411835-A Preparation of corticoids from 17-keto steroids THE UPJOHN COMPANY (US) 1983-10-25 US claimed
US-4404142-A Preparation of corticoids from 17-keto steroids THE UPJOHN COMPANY (US) 1983-09-13 US claimed
US-4401599-A Preparation of 21-halo steroids THE UPJOHN COMPANY (US) 1983-08-30 US claimed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-11780807-B2 Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor Kuleon, LLC (US) 2023-10-10 US disclosed
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR Kuleon, LLC (US) 2023-08-17 US disclosed
EP-3464317-B1 AMINOSTEROID DERIVATIVES AND PROCESS FOR PRODUCING SAME UNIV LAVAL (CA) 2023-04-26 EP disclosed
CN-114105939-B Transparent colorless liquid high-refractive-index monomer and application thereof 江苏集萃光敏电子材料研究所有限公司 2023-02-28 CN disclosed
US-11543750-B2 Lithographic printing plate precursor and method for producing lithographic printing plate FUJIFILM CORPORATION (JP) 2023-01-03 US disclosed
EP-0171037-A2 3-Carbonyl-1-aminoalkyl-1H-indoles useful as analgesics and preparation thereof STERLING WINTHROP INC. (US) 1986-02-12 EP disclosed
US-4357279-A Preparation of corticoids from 17-keto steroids THE UPJOHN COMPANY (US) 1982-11-02 US disclosed
US-4342702-A Metallated halogenated acetylene corticoid synthesis THE UPJOHN COMPANY (US) 1982-08-03 US disclosed
US-4101583-A Alpha-methylthio-alpha-(2-aminophenyl) acetaldehyde diloweralkyl acetals THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-07-18 US disclosed
US-4080341-A Carbazolenine and indole compounds THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-03-21 US disclosed
US-4067875-A Certain N-phenyl or N-pyridyl aza sulfonium salts THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1978-01-10 US disclosed
US-3992392-A Synthesis of indoles from anilines and intermediates therein THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110130482-A1 Process for preparing armatic thiophenyl ketones ACOT7, AGPAT2, COASY FFAR1 1578/4885PKM 799/4885MTNR1A 4740/4885
US-11780807-B2 Benzoselenophene, benzothiophene, and benzofuran analogs and methods of modulating the serotonin 5-HT2C receptor HTR2C, HTR2A, HTR3C FFAR1 530/4885PKM 4516/4885MTNR1A 124/4885
US-11833213-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A FFAR1 2426/4885PKM 4394/4885MTNR1A 1599/4885
US-20230257346-A1 BENZOSELENOPHENE AND SELENOPHENOPYRIDINE ANALOGS AND METHODS OF MODULATING THE SEROTONIN 5-HT2C RECEPTOR HTR2C, HTR2A, HTR3B FFAR1 812/4885PKM 4326/4885MTNR1A 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.