SCHEMBL3428602

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3430292	0.90	PTGER4 (0.61)	PTGER4SMN1; SMN2EPHX2NR1H4CACNA1H
	SCHEMBL3428221	0.87	PTGER4 (0.61)	PTGER4TP53SMN1; SMN2ALDH1A1GAA
	SCHEMBL3430587	0.83	KMT2A (0.49)	PTGER4GAAEPHX2NR1H4MAPT
	SCHEMBL3428215	0.82	PTGER4 (0.63)	PTGER4SMN1; SMN2CNR1FSCN1
	SCHEMBL3428482	0.81	PTGER4 (0.61)	PTGER4TP53SMN1; SMN2EPHX2TNF
	SCHEMBL7151503	0.81	PTGER4 (0.60)	PTGER4TP53SMN1; SMN2FSCN1
	SCHEMBL3759797	0.81	TDP1 (0.48)	PTGER4TP53SMN1; SMN2ALDH1A1GAA
	SCHEMBL24273140	0.80	PTGER4 (0.74)	PTGER4TP53SMN1; SMN2CACNA1H
	SCHEMBL28361137	0.79	MAPT (0.58)	PTGER4TP53TRPV1SMN1; SMN2EPHX2
	SCHEMBL3430489	0.79	PTGER4 (0.47)	PTGER4SMN1; SMN2MAPTCNR1FSCN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.