SCHEMBL3430489

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3428348	0.87	IDH1 (0.44)	PTGER4RAB9ACNR1NPC1KIT
	SCHEMBL3431802	0.86	PTGER4 (0.46)	PTGER4RAB9ACNR1KITBRAF
	SCHEMBL3432147	0.86	USP2 (0.52)	RAB9ANPC1MAPT
	SCHEMBL3430168	0.85	RAB9A (0.46)	PTGER4RAB9ASMN1; SMN2CNR1NPC1
	SCHEMBL3429688	0.82	MAPK1 (0.48)	PTGER4RAB9ASMN1; SMN2CNR1NPC1
	SCHEMBL12996462	0.82	RAB9A (0.43)	PTGER4RAB9ACYP1A2CYP2C9CYP2C19
	SCHEMBL3430292	0.79	PTGER4 (0.61)	PTGER4RAB9ASMN1; SMN2CNR1NPC1
	SCHEMBL3430287	0.79	PTGER4 (0.57)	PTGER4RAB9ACPT1AFSCN1NPC1
	SCHEMBL3428602	0.79	PTGER4 (0.63)	PTGER4SMN1; SMN2CNR1FSCN1MAPT
	SCHEMBL3430587	0.78	KMT2A (0.49)	PTGER4CNR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.