Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30004043 | 0.75 | MAPT (0.53) | EPHX2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23271783 | 0.75 | MAPT (0.53) | EPHX2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3431641 | 0.74 | RAB9A (0.59) | EPHX2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5820346 | 0.72 | MEN1 (0.47) | EPHX2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5821552 | 0.72 | MAPT (0.60) | EPHX2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL30002528 | 0.72 | MAPT (0.60) | EPHX2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23271652 | 0.72 | MAPT (0.60) | EPHX2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL5810491 | 0.70 | MEN1 (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL30004289 | 0.70 | MEN1 (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11881848 | 0.67 | MAPT (0.56) | MAPTKDM4ERECQLGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252569-B1 | ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS | JULIUS MAXIMILIANS UNIVERSITÄT WÜRZBURG (DE) | 2016-10-05 | — | — | EP | disclosed |
| EP-2252569-B1 | ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS | JULIUS MAXIMILIANS UNIVERSITÄT WÜRZBURG (DE) | 2016-10-05 | — | — | EP | disclosed |
| US-8877718-B2 | Antiinfective and antitumoral compounds isolated from tropical lianas | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2014-11-04 | — | — | US | disclosed |
| US-8877718-B2 | Antiinfective and antitumoral compounds isolated from tropical lianas | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2014-11-04 | — | — | US | disclosed |
| US-20110059911-A1 | Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas | JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) | 2011-03-10 | — | — | US | disclosed |
| US-20110059911-A1 | Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas | JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG (DE) | 2011-03-10 | — | — | US | disclosed |
| EP-2252569-A2 | ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS | Julius-Maximilians-Universität Würzburg (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2093207-A1 | Antiinfective and antitumoral compounds isolated from tropical lianas | Julius-Maximilians-Universität Würzburg (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-2093207-A1 | Antiinfective and antitumoral compounds isolated from tropical lianas | Julius-Maximilians-Universität Würzburg (DE) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009098082-A2 | ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009098082-A2 | ANTIINFECTIVE AND ANTITUMORAL COMPOUNDS ISOLATED FROM TROPICAL LIANAS | JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG (DE) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110059911-A1 | Antiinfective and Antitumoral Compounds Isolated From Tropical Lianas | NCL, SYNCRIP, MYC | EPHX2 3198/4885MAPT 4212/4885KDM4E 4021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.